BAY-1251152
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407914

CAS#: 1610358-56-9 (rotation +)

Description: (+)-Enitociclib; also known as BAY-1251152, (+)-BAY-1251152, is a CDK9 inhibitor.

Chemical Structure

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BAY-1251152
CAS# 1610358-56-9 (rotation +)
Instruction

Theoretical Analysis

MedKoo Cat#: 407914
Name: BAY-1251152
CAS#: 1610358-56-9 (rotation +)
Chemical Formula: C19H18F2N4O2S
Exact Mass: 404.11
Molecular Weight: 404.436
Elemental Analysis: C, 56.43; H, 4.49; F, 9.40; N, 13.85; O, 7.91; S, 7.93

Price and Availability

Size Price Availability Quantity
5mg USD 450 2 Weeks
10mg USD 750 2 Weeks
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Related CAS #: 1610358-53-6 (racemate)   1610358-56-9 (rotation +)   1610358-59-2 (roation -)   1610408-96-2 (R-isomer)   1610408-97-3 (S-isomer)   1610368-59-6 (R-isomer HCl)   1610368-60-9 (S-isomer HCl)    

Synonym: BAY-1251152; BAY 1251152; BAY1251152; (+)-BAY-1251152; (+)-Enitociclib

IUPAC/Chemical Name: (+)-5-Fluoro-4-(4-fluoro-2-methoxyphenyl)-N-[4-[(S-methylsulfonimidoyl)methyl]pyridin-2-yl]pyridin-2-amine

InChi Key: YZCUMZWULWOUMD-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H18F2N4O2S/c1-27-17-8-13(20)3-4-14(17)15-9-19(24-10-16(15)21)25-18-7-12(5-6-23-18)11-28(2,22)26/h3-10,22H,11H2,1-2H3,(H,23,24,25)

SMILES Code: N=S(CC1=CC(NC2=NC=C(F)C(C3=CC=C(F)C=C3OC)=C2)=NC=C1)(C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 97.2 240.21

Preparing Stock Solutions

The following data is based on the product molecular weight 404.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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WO 2014076091 A1