WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558115

CAS#: 18854-01-8

Description: Isoxathion, also known as SI-6711, is an organothiophosphate insecticide.

Chemical Structure

CAS# 18854-01-8

Theoretical Analysis

MedKoo Cat#: 558115
Name: Isoxathion
CAS#: 18854-01-8
Chemical Formula: C13H16NO4PS
Exact Mass: 313.05
Molecular Weight: 313.31
Elemental Analysis: C, 49.84; H, 5.15; N, 4.47; O, 20.43; P, 9.89; S, 10.23

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Karphos; HSDB6692; HSDB 6692; HSDB-6692; Isoxathion; SI-6711; SI 6711; SI6711;

IUPAC/Chemical Name: O,O-Diethyl O-5-phenylisoxazol-3-ylphosphorothioate


InChi Code: InChI=1S/C13H16NO4PS/c1-3-15-19(20,16-4-2)18-13-10-12(17-14-13)11-8-6-5-7-9-11/h5-10H,3-4H2,1-2H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 313.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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Reconstitution Calculator

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1: Sakaguchi K, Nagayama M, Masaoka T, Nishimura A, Kageyama K, Shirai M, Akahori F. Effects of fenthion, isoxathion, dichlorvos and propaphos on the serum cholinesterase isoenzyme patterns of dogs. Vet Hum Toxicol. 1997 Feb;39(1):1-5. PubMed PMID: 9004458.

2: Ageda S, Fuke C, Ihama Y, Miyazaki T. The stability of organophosphorus insecticides in fresh blood. Leg Med (Tokyo). 2006 May;8(3):144-9. Epub 2006 Mar 3. PubMed PMID: 16517205.

3: Thurman EM, Ferrer I, Zavitsanos P, Zweigenbaum JA. Analysis of isobaric pesticides in pepper with high-resolution liquid chromatography and mass spectrometry: complementary or redundant? J Agric Food Chem. 2013 Mar 13;61(10):2340-7. doi: 10.1021/jf304642g. Epub 2013 Jan 29. PubMed PMID: 23305249.

4: Kitamura K, Maruyama K, Hamano S, Kishi T, Kawakami T, Takahashi Y, Onodera S. Effect of hypochlorite oxidation on cholinesterase-inhibition assay of acetonitrile extracts from fruits and vegetables for monitoring traces of organophosphate pesticides. J Toxicol Sci. 2014 Feb;39(1):71-81. PubMed PMID: 24418711.

5: Kanno A, Kawakami T, Takahashi Y, Onodera S. Enhancement of anti-cholinesterase activity of aqueous samples by hypochlorite oxidation for monitoring traces of organophosphorus pesticides in water. J Toxicol Sci. 2012;37(2):389-400. PubMed PMID: 22467030.

6: Ohno K, Minami T, Matsui Y, Magara Y. Effects of chlorine on organophosphorus pesticides adsorbed on activated carbon: desorption and oxon formation. Water Res. 2008 Mar;42(6-7):1753-9. Epub 2007 Nov 6. PubMed PMID: 18048077.

7: Ueno E, Oshima H, Saito I, Matsumoto H. [Multiresidue analysis of organophosphorus pesticides in vegetables and fruits using dual-column GC-FPD, -NPD]. Shokuhin Eiseigaku Zasshi. 2001 Dec;42(6):385-93. Japanese. PubMed PMID: 11875824.

8: Yamanaka S, Yoshida M, Yamamura Y, Nishimura M, Takaesu Y. [A study on acute organophosphorus poisoning--changes in the activity and isoenzyme patterns of serum cholinesterase in human poisoning]. Nihon Eiseigaku Zasshi. 1993 Dec;48(5):955-65. Japanese. PubMed PMID: 8107298.

9: Takeuchi S, Iida M, Yabushita H, Matsuda T, Kojima H. In vitro screening for aryl hydrocarbon receptor agonistic activity in 200 pesticides using a highly sensitive reporter cell line, DR-EcoScreen cells, and in vivo mouse liver cytochrome P450-1A induction by propanil, diuron and linuron. Chemosphere. 2008 Dec;74(1):155-65. doi: 10.1016/j.chemosphere.2008.08.015. Epub 2008 Oct 5. PubMed PMID: 18835618.