Camphoric acid, (-)-
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MedKoo CAT#: 596944

CAS#: 560-09-8

Description: Camphoric acid, (-)- is a white crystallisable substance obtained from the oxidation of camphor. It exists in three optically different forms; the dextrorotatory one is obtained by the oxidation of dextrorotatory camphor and is used in pharmaceuticals.


Chemical Structure

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Camphoric acid, (-)-
CAS# 560-09-8

Theoretical Analysis

MedKoo Cat#: 596944
Name: Camphoric acid, (-)-
CAS#: 560-09-8
Chemical Formula: C10H16O4
Exact Mass: 200.1049
Molecular Weight: 200.23
Elemental Analysis: C, 59.98; H, 8.05; O, 31.96

Price and Availability

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1.0g USD 230.0 2 Weeks
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Synonym: Camphoric acid, (-)-; L-Camphoric acid;

IUPAC/Chemical Name: (1S,3R)-1,2,2-trimethylcyclopentane-1,3-dicarboxylic acid

InChi Key: LSPHULWDVZXLIL-QUBYGPBYSA-N

InChi Code: InChI=1S/C10H16O4/c1-9(2)6(7(11)12)4-5-10(9,3)8(13)14/h6H,4-5H2,1-3H3,(H,11,12)(H,13,14)/t6-,10+/m0/s1

SMILES Code: O=C([C@]1(C)C(C)(C)[C@H](C(O)=O)CC1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 200.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Zhao X, Nguyen ET, Hong AN, Feng P, Bu X. Chiral Isocamphoric Acid: Founding a Large Family of Homochiral Porous Materials. Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7101-7105. doi: 10.1002/anie.201802911. Epub 2018 May 17. PubMed PMID: 29774646.

2: Bandi MM, Akella VS, Singh DK, Singh RS, Mandre S. Hydrodynamic Signatures of Stationary Marangoni-Driven Surfactant Transport. Phys Rev Lett. 2017 Dec 29;119(26):264501. doi: 10.1103/PhysRevLett.119.264501. Epub 2017 Dec 28. PubMed PMID: 29328684.

3: Hou X, Xu T, Wang Y, Liu S, Tong J, Liu B. Superficial Chiral Etching on Achiral Metal-Organic Framework for Enantioselective Sorption. ACS Appl Mater Interfaces. 2017 Sep 20;9(37):32264-32269. doi: 10.1021/acsami.7b10147. Epub 2017 Sep 5. PubMed PMID: 28841003.

4: Boniface PK, Baptista Ferreira S, Roland Kaiser C. Current state of knowledge on the traditional uses, phytochemistry, and pharmacology of the genus Hymenaea. J Ethnopharmacol. 2017 Jul 12;206:193-223. doi: 10.1016/j.jep.2017.05.024. Epub 2017 May 21. Review. PubMed PMID: 28536059.

5: Cai K, Zhao N, Zhang N, Sun FX, Zhao Q, Zhu GS. A Homochiral Multifunctional Metal-Organic Framework with Rod-Shaped Secondary Building Units. Nanomaterials (Basel). 2017 Apr 21;7(4). pii: E88. doi: 10.3390/nano7040088. PubMed PMID: 28430135; PubMed Central PMCID: PMC5408180.

6: Lam J, Günther BA, Farrell JM, Eisenberger P, Bestvater BP, Newman PD, Melen RL, Crudden CM, Stephan DW. Chiral carbene-borane adducts: precursors for borenium catalysts for asymmetric FLP hydrogenations. Dalton Trans. 2016 Oct 21;45(39):15303-15316. Epub 2016 Jul 7. PubMed PMID: 27383522.

7: Zhang MD, Shi ZQ, Chen MD, Zheng HG. Chiral crystallization and optical properties of three metal complexes based on two non-centrosymmetric tripodal ligands. Dalton Trans. 2015 Mar 28;44(12):5818-25. doi: 10.1039/c5dt00292c. PubMed PMID: 25715030.

8: Qin L, Wang ZJ, Wang T, Zheng HG, Chen JX. Coligand-directed synthesis of five Co(II)/Ni(II) coordination polymers with a neutral tetradentate ligand: syntheses, crystal structures, and properties. Dalton Trans. 2014 Sep 7;43(33):12528-35. doi: 10.1039/c4dt01535e. PubMed PMID: 25004124.

9: Gu ZG, Bürck J, Bihlmeier A, Liu J, Shekhah O, Weidler PG, Azucena C, Wang Z, Heissler S, Gliemann H, Klopper W, Ulrich AS, Wöll C. Oriented circular dichroism analysis of chiral surface-anchored metal-organic frameworks grown by liquid-phase epitaxy and upon loading with chiral guest compounds. Chemistry. 2014 Aug 4;20(32):9879-82. doi: 10.1002/chem.201403524. Epub 2014 Jun 17. PubMed PMID: 24938623.

10: Fei ZX, Zhang M, Zhang JH, Yuan LM. Chiral metal-organic framework used as stationary phases for capillary electrochromatography. Anal Chim Acta. 2014 Jun 9;830:49-55. doi: 10.1016/j.aca.2014.04.054. Epub 2014 May 1. PubMed PMID: 24856511.

11: Jeon JH, Yang JY, Lee HS. Evaluation of the acaricidal toxicities of camphor and its structural analogues against house dust mites by the impregnated fabric disc method. Pest Manag Sci. 2014 Jul;70(7):1030-2. doi: 10.1002/ps.3769. Epub 2014 Mar 26. PubMed PMID: 24616046.

12: Bisht KK, Patel P, Rachuri Y, Eringathodi S. Binary co-crystals of the active pharmaceutical ingredient 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene and camphoric acid. Acta Crystallogr B Struct Sci Cryst Eng Mater. 2014 Feb;70(Pt 1):63-71. doi: 10.1107/S2052520613031260. Epub 2014 Jan 16. PubMed PMID: 24441129.

13: Bisht KK, Suresh E. Spontaneous resolution to absolute chiral induction: pseudo-Kagomé type homochiral Zn(II)/Co(II) coordination polymers with achiral precursors. J Am Chem Soc. 2013 Oct 23;135(42):15690-3. doi: 10.1021/ja4075369. Epub 2013 Oct 14. PubMed PMID: 24107095.

14: Dang DB, An B, Bai Y, Zheng GS, Niu JY. Three-dimensional homochiral manganese-lanthanide frameworks based on chiral camphorates with multi-coordination modes. Chem Commun (Camb). 2013 Mar 18;49(22):2243-5. doi: 10.1039/c3cc37680j. PubMed PMID: 23396508.

15: Xie SM, Zhang XH, Zhang ZJ, Zhang M, Jia J, Yuan LM. A 3-D open-framework material with intrinsic chiral topology used as a stationary phase in gas chromatography. Anal Bioanal Chem. 2013 Apr;405(10):3407-12. doi: 10.1007/s00216-013-6714-7. Epub 2013 Jan 30. PubMed PMID: 23361228.

16: Husár B, Moszner N, Lukáč I. Synthesis and photooxidation of styrene copolymer bearing camphorquinone pendant groups. Beilstein J Org Chem. 2012;8:337-43. doi: 10.3762/bjoc.8.37. Epub 2012 Mar 6. PubMed PMID: 22509202; PubMed Central PMCID: PMC3326610.

17: Adalder TK, Adarsh NN, Sankolli R, Dastidar P. Chiral gels derived from secondary ammonium salts of (1R,3S)-(+)-camphoric acid. Beilstein J Org Chem. 2010 Sep 21;6:848-58. doi: 10.3762/bjoc.6.100. PubMed PMID: 20978610; PubMed Central PMCID: PMC2956458.

18: Zhao SQ, Guo M, Zhang M, Wang XG, Chang S. [Preparation and spectroscopy properties of Eu2 (CA)3 (phen)2 doped Eu3+/TiO2 nano-powders]. Guang Pu Xue Yu Guang Pu Fen Xi. 2010 Aug;30(8):2187-91. Chinese. PubMed PMID: 20939336.

19: Sun ML, Zhang J, Lin QP, Yin PX, Yao YG. Multifunctional homochiral lanthanide camphorates with mixed achiral terephthalate ligands. Inorg Chem. 2010 Oct 18;49(20):9257-64. doi: 10.1021/ic1007445. PubMed PMID: 20845984.

20: Chen ZF, Liang H. Progresses in TCM metal-based antitumour agents. Anticancer Agents Med Chem. 2010 Jun;10(5):412-23. Review. PubMed PMID: 20545619.