WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596943

CAS#: 478-14-8

Description: Capaurine is an alkaloid isolated from root tubers of Stephania kwangsiensis H.S. Lo.

Chemical Structure

CAS# 478-14-8

Theoretical Analysis

MedKoo Cat#: 596943
Name: Capaurine
CAS#: 478-14-8
Chemical Formula: C21H25NO5
Exact Mass: 371.1733
Molecular Weight: 371.43
Elemental Analysis: C, 67.91; H, 6.78; N, 3.77; O, 21.54

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Capaurine; (-)-Capaurine; NSC 404532; NSC-404532; NSC404532;

IUPAC/Chemical Name: (S)-2,3,9,10-tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-1-ol


InChi Code: InChI=1S/C21H25NO5/c1-24-16-6-5-12-9-15-18-13(10-17(25-2)21(27-4)19(18)23)7-8-22(15)11-14(12)20(16)26-3/h5-6,10,15,23H,7-9,11H2,1-4H3/t15-/m0/s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 371.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Zuo AX, Li L, Ma YS, Rao GX. [Akaloids from roots of Stephania dentifolia]. Zhongguo Zhong Yao Za Zhi. 2013 Feb;38(4):574-7. Chinese. PubMed PMID: 23713286.

2: Galan A, Cervero F, Laird JM. Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain. Brain Res Mol Brain Res. 2003 Aug 19;116(1-2):126-34. PubMed PMID: 12941468.

3: Min ZD, Zhong SM. [Studies on the alkaloids of Stephania kwangsiensis H. S. Lo (author's transl)]. Yao Xue Xue Bao. 1980 Sep;15(9):532-7. Chinese. PubMed PMID: 7234425.

4: Shimanouchi H, Sasada Y, Ihara M, Kametani T. The crystal structure of capaurine hydrobromide. Acta Crystallogr B. 1969 Jul 15;25(7):1310-9. PubMed PMID: 5819640.

5: Kametani T, Ihara M, Fukumoto K, Yagi H. Structural determination of capaurimine and capaurine. Tetrahedron Lett. 1968 Aug;(40):4251-4. PubMed PMID: 5671794.