WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562996
Description: YCW-E11 is a inhibitor of antiapoptotic Bcl-2 family proteins.
MedKoo Cat#: 562996
Chemical Formula: C21H19ClN4
Exact Mass: 362.1298
Molecular Weight: 362.86
Elemental Analysis: C, 69.51; H, 5.28; Cl, 9.77; N, 15.44
This product is not in stock, which may be available by custom synthesis.
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Synonym: YCW-E11; YCW E11; YCWE11;
IUPAC/Chemical Name: N-(2-(3-(3,5-dichlorophenyl)ureido)ethyl)-3-(2-(3,4-dihydroxyphenoxy)phenyl)thiophene-2-sulfonamide
InChi Key: YCTPOOSUMJYWMU-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H18N4.ClH/c1-25(2)20-14-19(16-9-11-22-12-10-16)21(24-23-20)18-8-7-15-5-3-4-6-17(15)13-18;/h3-14H,1-2H3;1H
SMILES Code: CN(C)C1=NN=C(C2=CC(C=CC=C3)=C3C=C2)C(C4=CC=NC=C4)=C1.Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 362.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Yang C, Chen S, Zhou M, Li Y, Li Y, Zhang Z, Liu Z, Ba Q, Li J, Wang H, Yan X, Ma D, Wang R. Development of 3-phenyl-N-(2-(3-phenylureido)ethyl)-thiophene-2-sulfonamide compounds as inhibitors of antiapoptotic Bcl-2 family proteins. ChemMedChem. 2014 Jul;9(7):1436-52. doi: 10.1002/cmdc.201400058. Epub 2014 Apr 29. PubMed PMID: 24782462.