L-Aspoxicillin trihydrate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596932

CAS#: 63358-51-0

Description: L-Aspoxicillin trihydrate is a bioactive chemical.

Chemical Structure

img
L-Aspoxicillin trihydrate
CAS# 63358-51-0
Instruction

Theoretical Analysis

MedKoo Cat#: 596932
Name: L-Aspoxicillin trihydrate
CAS#: 63358-51-0
Chemical Formula: C21H33N5O10S
Exact Mass: 0.00
Molecular Weight: 547.580
Elemental Analysis: C, 46.06; H, 6.07; N, 12.79; O, 29.22; S, 5.85

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: L-Aspoxicillin trihydrate; ASPC;

IUPAC/Chemical Name: (5R,6R)-6-((S)-4-amino-N-((R)-2-amino-1-(4-hydroxyphenyl)-2-oxoethyl)-2-(methylamino)-4-oxobutanamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate

InChi Key: PHVWVLKMCNQOTH-QPXMJODCSA-N

InChi Code: InChI=1S/C21H27N5O7S.3H2O/c1-21(2)15(20(32)33)26-18(31)14(19(26)34-21)25(17(30)11(24-3)8-12(22)28)13(16(23)29)9-4-6-10(27)7-5-9;;;/h4-7,11,13-15,19,24,27H,8H2,1-3H3,(H2,22,28)(H2,23,29)(H,32,33);3*1H2/t11-,13+,14+,15?,19+;;;/m0.../s1

SMILES Code: O=C(N)[C@@H](C1=CC=C(O)C=C1)N(C([C@H](CC(N)=O)NC)=O)[C@H]2[C@@]3([H])SC(C)(C)C(C(O)=O)N3C2=O.[H]O[H].[H]O[H].[H]O[H]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 547.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Lim SC, Androga GO, Knight DR, Moono P, Foster NF, Riley TV. Antimicrobial susceptibility of Clostridium difficile isolated from food and environmental sources in Western Australia. Int J Antimicrob Agents. 2018 May 23. pii: S0924-8579(18)30144-4. doi: 10.1016/j.ijantimicag.2018.05.013. [Epub ahead of print] PubMed PMID: 29802886.

2: Du Y, Wang J, Zhu F, Mai D, Xiang Z, Chen J, Guo R. Comprehensive assessment of three typical antibiotics on cyanobacteria (Microcystis aeruginosa): The impact and recovery capability. Ecotoxicol Environ Saf. 2018 Sep 30;160:84-93. doi: 10.1016/j.ecoenv.2018.05.035. Epub 2018 May 21. PubMed PMID: 29793205.

3: Kaliyaperumal K, Grove JI, Delahay RM, Griffiths WJH, Duckworth A, Aithal GP. Pharmacogenomics of drug-induced liver injury (DILI): Molecular biology to clinical applications. J Hepatol. 2018 May 21. pii: S0168-8278(18)32059-2. doi: 10.1016/j.jhep.2018.05.013. [Epub ahead of print] Review. PubMed PMID: 29792895.

4: Mariage M, Sabbagh C, Yzet T, Dupont H, NTouba A, Regimbeau JM. Distinguishing fecal appendicular peritonitis from purulent appendicular peritonitis. Am J Emerg Med. 2018 Apr 9. pii: S0735-6757(18)30289-4. doi: 10.1016/j.ajem.2018.04.014. [Epub ahead of print] PubMed PMID: 29779677.

5: Wohlmuth da Silva S, Arenhart Heberle AN, Pereira Santos A, Siqueira Rodrigues MA, Pérez-Herranz V, Moura Bernardes A. Antibiotics mineralization by electrochemical and UV-based hybrid processes: evaluation of the synergistic effect. Environ Technol. 2018 May 29:1-11. doi: 10.1080/09593330.2018.1478453. [Epub ahead of print] PubMed PMID: 29770731.

6: Boukhelkhal A, Benkortbi O, Hamadache M. Use of an anionic surfactant for the sorption of a binary mixture of antibiotics from aqueous solutions. Environ Technol. 2018 May 10:1-9. doi: 10.1080/09593330.2018.1472301. [Epub ahead of print] PubMed PMID: 29717627.

7: Jafari K, Heidari M, Rahmanian O. Wastewater treatment for Amoxicillin removal using magnetic adsorbent synthesized by ultrasound process. Ultrason Sonochem. 2018 Jul;45:248-256. doi: 10.1016/j.ultsonch.2018.03.018. Epub 2018 Mar 30. PubMed PMID: 29705319.

8: da Silva DC, Oliveira CC. Development of Micellar HPLC-UV Method for Determination of Pharmaceuticals in Water Samples. J Anal Methods Chem. 2018 Mar 1;2018:9143730. doi: 10.1155/2018/9143730. eCollection 2018. PubMed PMID: 29686934; PubMed Central PMCID: PMC5852859.

9: Sandberg JK, Hulett-Bowling R, Khanna G. Case 253: Thrombosed Umbilical Venous Varix in an Infant. Radiology. 2018 May;287(2):719-724. doi: 10.1148/radiol.2018160106. PubMed PMID: 29668410.

10: Koetsveld J, Manger A, Hoornstra D, Draga RO, Oei A, Kolyasnikova NM, Toporkova MG, Sarksyan DS, Wagemakers A, Platonov AE, Hovius JW. In vitro antimicrobial susceptibility of clinical isolates of Borrelia miyamotoi. Antimicrob Agents Chemother. 2018 Apr 16. pii: AAC.00419-18. doi: 10.1128/AAC.00419-18. [Epub ahead of print] PubMed PMID: 29661882.

11: Paul P, Sänger-van de Griend C, Adams E, Van Schepdael A. A simple, low-cost and robust capillary zone electrophoresis method with capacitively coupled contactless conductivity detection for the routine determination of four selected penicillins in money-constrained laboratories. Electrophoresis. 2018 Apr 12. doi: 10.1002/elps.201800033. [Epub ahead of print] PubMed PMID: 29645291.

12: Kim C, Ryu HD, Chung EG, Kim Y. Determination of 18 veterinary antibiotics in environmental water using high-performance liquid chromatography-q-orbitrap combined with on-line solid-phase extraction. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 May 1;1084:158-165. doi: 10.1016/j.jchromb.2018.03.038. Epub 2018 Mar 27. PubMed PMID: 29604614.

13: Edoo Z, Iannazzo L, Compain F, Li de la Sierra Gallay I, van Tilbeurgh H, Fonvielle M, Bouchet F, Le Run E, Mainardi JL, Arthur M, Ethève-Quelquejeu M, Hugonnet JE. Synthesis of Avibactam Derivatives and Activity on β-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria. Chemistry. 2018 Jun 7;24(32):8081-8086. doi: 10.1002/chem.201800923. Epub 2018 May 14. PubMed PMID: 29601108.

14: Shi X, Yeap TS, Huang S, Chen J, Ng HY. Pretreatment of saline antibiotic wastewater using marine microalga. Bioresour Technol. 2018 Jun;258:240-246. doi: 10.1016/j.biortech.2018.02.110. Epub 2018 Feb 24. PubMed PMID: 29529564.

15: Wang J, Guo H, Cao C, Zhao W, Kwok LY, Zhang H, Zhang W. Characterization of the Adaptive Amoxicillin Resistance of Lactobacillus casei Zhang by Proteomic Analysis. Front Microbiol. 2018 Feb 20;9:292. doi: 10.3389/fmicb.2018.00292. eCollection 2018. PubMed PMID: 29515561; PubMed Central PMCID: PMC5826216.

16: Li Q, Wang H, Xu Y, Bai X, Wang J, Zhang Z, Liu X, Miao Y, Zhang L, Li X, Zou N, Yan G, Chen X, Zhang J, Fu S, Fan R, Xu J, Li J, Xiong Y. Multidrug-Resistant Escherichia albertii: Co-occurrence of β-Lactamase and MCR-1 Encoding Genes. Front Microbiol. 2018 Feb 16;9:258. doi: 10.3389/fmicb.2018.00258. eCollection 2018. PubMed PMID: 29503643; PubMed Central PMCID: PMC5820351.

17: Akrami-Mohajeri F, Derakhshan Z, Ferrante M, Hamidiyan N, Soleymani M, Conti GO, Tafti RD. The prevalence and antimicrobial resistance of Listeria spp in raw milk and traditional dairy products delivered in Yazd, central Iran (2016). Food Chem Toxicol. 2018 Apr;114:141-144. doi: 10.1016/j.fct.2018.02.006. Epub 2018 Feb 12. PubMed PMID: 29448094.

18: Moura D, Barcelos V, Samanamud GRL, França AB, Lofrano R, Loures CCA, Naves LLR, Amaral MS, Naves FL. Normal boundary intersection applied as multivariate and multiobjective optimization in the treatment of amoxicillin synthetic solution. Environ Monit Assess. 2018 Feb 14;190(3):140. doi: 10.1007/s10661-018-6523-8. PubMed PMID: 29445954.

19: Romain O. Antibiothérapie des infections néonatales bactériennes précoces chez les nouveau-nés nés à partir de 34 semaines d’aménorrhée. Arch Pediatr. 2017 Dec;24 Suppl 3:S24-S28. doi: 10.1016/S0929-693X(18)30041-1. French. PubMed PMID: 29433694.

20: Kafaei R, Papari F, Seyedabadi M, Sahebi S, Tahmasebi R, Ahmadi M, Sorial GA, Asgari G, Ramavandi B. Occurrence, distribution, and potential sources of antibiotics pollution in the water-sediment of the northern coastline of the Persian Gulf, Iran. Sci Total Environ. 2018 Jun 15;627:703-712. doi: 10.1016/j.scitotenv.2018.01.305. Epub 2018 Feb 3. PubMed PMID: 29426195.