UK-88947 HCl

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MedKoo CAT#: 596903

CAS#: 137015-76-0 (HCl)

Description: UK 88947 is a protease inhibitor.


Price and Availability

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Pricing updated 2020-10-31. Prices are subject to change without notice.

UK 88947 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596903
Name: UK-88947 HCl
CAS#: 137015-76-0 (HCl)
Chemical Formula: C40H60ClN5O7
Exact Mass:
Molecular Weight: 758.39
Elemental Analysis: C, 63.35; H, 7.97; Cl, 4.67; N, 9.23; O, 14.77


Related CAS #: 137015-76-0 (HCl)    

Synonym: UK 88947; UK-88947; UK88947; UK-88,947; UK 88,947; UK88,947;

IUPAC/Chemical Name: (3S)-3-((S)-2-(1-aminocyclohexane-1-carboxamido)-3-phenylpropanamido)-4-(((2S,5R)-3-hydroxy-5-(isobutylcarbamoyl)-7-methyl-1-phenyloctan-2-yl)amino)-4-oxobutanoic acid hydrochloride

InChi Key: OSKPXYCTBWIRIE-YVITZFCESA-N

InChi Code: InChI=1S/C40H59N5O7.ClH/c1-26(2)20-30(36(49)42-25-27(3)4)23-34(46)31(21-28-14-8-5-9-15-28)43-38(51)33(24-35(47)48)44-37(50)32(22-29-16-10-6-11-17-29)45-39(52)40(41)18-12-7-13-19-40;/h5-6,8-11,14-17,26-27,30-34,46H,7,12-13,18-25,41H2,1-4H3,(H,42,49)(H,43,51)(H,44,50)(H,45,52)(H,47,48);1H/t30-,31+,32+,33+,34?;/m1./s1

SMILES Code: O=C(O)C[C@@H](C(N[C@@H](CC1=CC=CC=C1)C(O)C[C@H](C(NCC(C)C)=O)CC(C)C)=O)NC([C@H](CC2=CC=CC=C2)NC(C3(N)CCCCC3)=O)=O.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Nagy K, Young M, Baboonian C, Merson J, Whittle P, Oroszlan S. Antiviral activity of human immunodeficiency virus type 1 protease inhibitors in a single cycle of infection: evidence for a role of protease in the early phase. J Virol. 1994 Feb;68(2):757-65. PubMed PMID: 8289379; PubMed Central PMCID: PMC236512.

2: Baboonian C, Dalgleish A, Bountiff L, Gross J, Oroszlan S, Rickett G, Smith-Burchnell C, Troke P, Merson J. HIV-1 proteinase is required for synthesis of pro-viral DNA. Biochem Biophys Res Commun. 1991 Aug 30;179(1):17-24. Erratum in: Biochem Biophys Res Commun 1992 Sep 16;187(2):1200. PubMed PMID: 1652947.