Lamtidine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559062

CAS#: 73278-54-3

Description: Lamtidine is a biochemical.


Chemical Structure

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Lamtidine
CAS# 73278-54-3

Theoretical Analysis

MedKoo Cat#: 559062
Name: Lamtidine
CAS#: 73278-54-3
Chemical Formula: C18H28N6O
Exact Mass: 344.2325
Molecular Weight: 344.46
Elemental Analysis: C, 62.76; H, 8.19; N, 24.40; O, 4.64

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: AH-22216; AH22216; AH 22216

IUPAC/Chemical Name: 1-(m-(3-((3-Amino-1-methyl-1H-1,2,4-triazol-5-yl)amino)propoxy)benzyl)piperidine

InChi Key: NRIGRKAXOLMTSK-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H28N6O/c1-23-18(21-17(19)22-23)20-9-6-12-25-16-8-5-7-15(13-16)14-24-10-3-2-4-11-24/h5,7-8,13H,2-4,6,9-12,14H2,1H3,(H3,19,20,21,22)

SMILES Code: CN1N=C(N)N=C1NCCCOC2=CC(CN3CCCCC3)=CC=C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 344.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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8: Orsetti M. Histamine H2-receptor blocking activity of ranitidine and lamtidine analogues containing aminomethyl-substituted aliphatic systems. Agents Actions. 1988 Dec;25(3-4):291-5. PubMed PMID: 2905866.

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10: Orsetti M, Sorba G. Pharmacological profile of new histamine H2-receptor antagonists related to cimetidine, ranitidine and lamtidine. J Pharm Pharmacol. 1988 Jan;40(1):31-4. PubMed PMID: 2896770.

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12: Menez I, Gespach C, Emami S, Rosselin G. Irreversible and specific inactivation by AH 22216 of histamine H2 receptors in the human gastric cancer cell line HGT-1. Biochem Biophys Res Commun. 1983 Oct 14;116(1):251-7. PubMed PMID: 6315003.

13: Gespach C, Menez I, Emami S. Potent and specific blockade by AH 22216 of histamine-H2-receptor-mediated acid secretion in isolated rabbit gastric cells. Biosci Rep. 1983 Sep;3(9):871-8. PubMed PMID: 6640083.

14: Stables R, Daly MJ, Humphray JM. Comparison of antisecretory potency and duration of action of the H2-receptor antagonists AH 22216, cimetidine, ranitidine and SK & F 93479 in the dog. Agents Actions. 1983 Apr;13(2-3):166-9. PubMed PMID: 6135321.