Cyclanoline chloride

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MedKoo CAT#: 596843

CAS#: 17472-50-3 (Cl-)

Description: Cyclanoline chloride is a bioactive chemical.


Chemical Structure

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Cyclanoline chloride
CAS# 17472-50-3 (Cl-)

Theoretical Analysis

MedKoo Cat#: 596843
Name: Cyclanoline chloride
CAS#: 17472-50-3 (Cl-)
Chemical Formula: C20H25ClNO4
Exact Mass: 378.15
Molecular Weight: 378.870
Elemental Analysis: C, 63.40; H, 6.65; Cl, 9.36; N, 3.70; O, 16.89

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 17472-50-3 (Cl-)   18556-27-9 (free base)  

Synonym: Cyclanoline chloride; Cissamine chloride; l-alpha-N-Methylscoulerine;

IUPAC/Chemical Name: 13a-alpha-Berbinium, 2,9-dihydroxy-3,10-dimethoxy-7-methyl-, chloride

InChi Key: QWRAOQCEPZKINL-KTWHHOSASA-O

InChi Code: InChI=1S/C20H23NO4.ClH/c1-21-7-6-13-9-19(25-3)17(22)10-14(13)16(21)8-12-4-5-18(24-2)20(23)15(12)11-21;/h4-5,9-10,16H,6-8,11H2,1-3H3,(H-,22,23);1H/q;-1/p+1/t16-,21-;/m1./s1

SMILES Code: COc1ccc(C2)c(C[N@+]3(C)[C@H]2c4cc(O)c(OC)cc4CC3)c1O.[ClH-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 378.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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2: Ingkaninan K, Phengpa P, Yuenyongsawad S, Khorana N. Acetylcholinesterase inhibitors from Stephania venosa tuber. J Pharm Pharmacol. 2006 May;58(5):695-700. PubMed PMID: 16640839.

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4: Tanahashi T, Su U, Nagakura N, Nayeshiro H. Quaternary isoquinoline alkaloids from Stephania cepharantha. Chem Pharm Bull (Tokyo). 2000 Mar;48(3):370-3. PubMed PMID: 10726860.

5: Yang YF, Zhao SX, Dong SS, Liu C. [Dual-wavelength TLC densitometric determination of alkaloids in radix Stephaniae tetrandrae]. Zhong Yao Tong Bao. 1988 Dec;13(12):36-7, 59-60. Chinese. PubMed PMID: 3255530.

6: TOMITA M, IBUKA T, TSUYAMA K. [STUDIES ON THE ALKALOIDS OF MENISPERMACEOUS PLANTS. CCVI. ALKALOIDS OF FORMOSAN STEPHANIA JAPONICA MIERS. (3). THE ISOLATION OF WATER-SOLUBLE QUATERNARY BASE, CYCLANOLINE]. Yakugaku Zasshi. 1964 Aug;84:776-8. Japanese. PubMed PMID: 14236247.