WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562963
CAS#: 1077626-52-8
Description: CAY10589 is an inhibitor of mPGES-1.
MedKoo Cat#: 562963
Name: CAY10589
CAS#: 1077626-52-8
Chemical Formula: C25H28ClN3O2S
Exact Mass: 469.1591
Molecular Weight: 470.02
Elemental Analysis: C, 63.88; H, 6.00; Cl, 7.54; N, 8.94; O, 6.81; S, 6.82
Synonym: CAY10589; CAY-10589; CAY 10589;
IUPAC/Chemical Name: 2-[[4-[([1,1′-Biphenyl]-4-ylmethyl)amino]-6-chloro-2-pyrimidinyl]thio]-octanoic acid
InChi Key: FQMPYBCEABTPIK-UHFFFAOYSA-N
InChi Code: InChI=1S/C25H28ClN3O2S/c1-2-3-4-8-11-21(24(30)31)32-25-28-22(26)16-23(29-25)27-17-18-12-14-20(15-13-18)19-9-6-5-7-10-19/h5-7,9-10,12-16,21H,2-4,8,11,17H2,1H3,(H,30,31)(H,27,28,29)
SMILES Code: CCCCCCC(SC1=NC(Cl)=CC(NCC2=CC=C(C3=CC=CC=C3)C=C2)=N1)C(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 470.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Wiegard A, Hanekamp W, Griessbach K, Fabian J, Lehr M. Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1. Eur J Med Chem. 2012 Feb;48:153-63. doi: 10.1016/j.ejmech.2011.12.009. Epub 2011 Dec 9. PubMed PMID: 22209272.
