R 487

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596834

CAS#: 132041-94-2

Description: R 487 is a bioactive chemical.


Chemical Structure

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R 487
CAS# 132041-94-2

Theoretical Analysis

MedKoo Cat#: 596834
Name: R 487
CAS#: 132041-94-2
Chemical Formula: C39H56N8O10S
Exact Mass: 828.384
Molecular Weight: 828.98
Elemental Analysis: C, 56.51; H, 6.81; N, 13.52; O, 19.30; S, 3.87

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: R 487; R-487; R487; Asp-ser-phe-phe-beta-ala-leu-met-NH2;

IUPAC/Chemical Name: (5S,8S,15S,18S,21S,24S)-24-amino-15,18-dibenzyl-5-carbamoyl-21-(hydroxymethyl)-8-isobutyl-7,10,14,17,20,23-hexaoxo-2-thia-6,9,13,16,19,22-hexaazahexacosan-26-oic acid

InChi Key: YASUUTPQYSSIAK-HPMAGDRPSA-N

InChi Code: InChI=1S/C39H56N8O10S/c1-23(2)18-28(37(55)44-27(34(41)52)15-17-58-3)43-32(49)14-16-42-36(54)29(19-24-10-6-4-7-11-24)45-38(56)30(20-25-12-8-5-9-13-25)46-39(57)31(22-48)47-35(53)26(40)21-33(50)51/h4-13,23,26-31,48H,14-22,40H2,1-3H3,(H2,41,52)(H,42,54)(H,43,49)(H,44,55)(H,45,56)(H,46,57)(H,47,53)(H,50,51)/t26-,27-,28-,29-,30-,31-/m0/s1

SMILES Code: CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CCNC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CC=CC=C2)NC([C@H](CO)NC([C@H](CC(O)=O)N)=O)=O)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 828.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Fahrenholtz IL, Sjödin A, Benardot D, Tornberg ÅB, Skouby S, Faber J, Sundgot-Borgen JK, Melin AK. Within-day energy deficiency and reproductive function in female endurance athletes. Scand J Med Sci Sports. 2018 Mar;28(3):1139-1146. doi: 10.1111/sms.13030. Epub 2018 Feb 5. PubMed PMID: 29205517.

2: Man Y, Mengmeng L, Lezhi L, Ting M, Jingping Z. The psychological problems and related influential factors of left-behind adolescents (LBA) in Hunan, China: a cross sectional study. Int J Equity Health. 2017 Sep 2;16(1):163. doi: 10.1186/s12939-017-0639-2. PubMed PMID: 28865480; PubMed Central PMCID: PMC5581416.

3: Takahashi Y, Fukushima Y, Kondo K, Ichihashi M. Facial skin photo-aging and development of hyperpigmented spots from children to middle-aged Japanese woman. Skin Res Technol. 2017 Nov;23(4):613-618. doi: 10.1111/srt.12380. Epub 2017 Jun 1. PubMed PMID: 28568473.

4: Danielak D, Komosa A, Tomczak A, Graczyk-Szuster A, Lesiak M, Główka F, Karaźniewicz-Łada M. Determinants of high on-treatment platelet reactivity and agreement between VerifyNow and Multiplate assays. Scand J Clin Lab Invest. 2017 May;77(3):190-198. doi: 10.1080/00365513.2017.1286686. Epub 2017 Feb 24. PubMed PMID: 28276728.

5: Lockie RG, Jeffriess MD, McGann TS, Callaghan SJ, Schultz AB. Planned and reactive agility performance in semiprofessional and amateur basketball players. Int J Sports Physiol Perform. 2014 Sep;9(5):766-71. doi: 10.1123/ijspp.2013-0324. Epub 2013 Nov 14. PubMed PMID: 24231129.

6: Santos-Rebouças CB, Belet S, Guedes de Almeida L, Ribeiro MG, Medina-Acosta E, Bahia PR, Alves da Silva AF, Lima dos Santos F, Borges de Lacerda GC, Pimentel MM, Froyen G. A novel in-frame deletion affecting the BAR domain of OPHN1 in a family with intellectual disability and hippocampal alterations. Eur J Hum Genet. 2014 May;22(5):644-51. doi: 10.1038/ejhg.2013.216. Epub 2013 Oct 9. PubMed PMID: 24105372; PubMed Central PMCID: PMC3992576.

7: Gratacós-Cubarsí M, Sárraga C, Clariana M, Regueiro JA, Castellari M. Analysis of vitamin B1 in dry-cured sausages by hydrophilic interaction liquid chromatography (HILIC) and diode array detection. Meat Sci. 2011 Mar;87(3):234-8. doi: 10.1016/j.meatsci.2010.10.017. Epub 2010 Oct 27. PubMed PMID: 21078548.

8: Williams B, Diehr P, LoGerfo J. Evaluating a preventive services index to adjust for healthy behaviors in observational studies of older adults. Prev Chronic Dis. 2010 Sep;7(5):A110. Epub 2010 Aug 15. PubMed PMID: 20712937; PubMed Central PMCID: PMC2938404.

9: Goldsmith ME. Postpartum depression screening by family nurse practitioners. J Am Acad Nurse Pract. 2007 Jun;19(6):321-7. PubMed PMID: 17535342.

10: Poon RT, Lau C, Pang R, Ng KK, Yuen J, Fan ST. High serum vascular endothelial growth factor levels predict poor prognosis after radiofrequency ablation of hepatocellular carcinoma: importance of tumor biomarker in ablative therapies. Ann Surg Oncol. 2007 Jun;14(6):1835-45. Epub 2007 Apr 4. PubMed PMID: 17406950.

11: Jo KH, Son BK. [The relationship of uncertainty, hope and quality of life in patients with breast cancer]. Taehan Kanho Hakhoe Chi. 2004 Dec;34(7):1184-93. Korean. PubMed PMID: 15687759.

12: McCarter-Spaulding DE, Kearney MH. Parenting self-efficacy and perception of insufficient breast milk. J Obstet Gynecol Neonatal Nurs. 2001 Sep-Oct;30(5):515-22. PubMed PMID: 11572532.

13: Yang L, Zhao Y, Xu Y, Jin X, Weng S, Tian W, Wu J, Xu G. Complexation of trivalent lanthanide cations by D-ribose in the solid state. The crystal structure and FT-IR study of PrCl3-alpha-D-ribopyranose-5H2O. Carbohydr Res. 2001 Aug 23;334(2):91-5. PubMed PMID: 11502264.

14: Rosenthal AJ, Sanders KM, McMurtry CT, Jacobs MA, Thompson DD, Gheorghiu D, Little KL, Adler RA. Is malnutrition overdiagnosed in older hospitalized patients? Association between the soluble interleukin-2 receptor and serum markers of malnutrition. J Gerontol A Biol Sci Med Sci. 1998 Mar;53(2):M81-6. PubMed PMID: 9520912.

15: Daniel EE, Parrish MB, Watson EG, Fox-Threlkeld JE, Regoli D, Rainsford KD. The tachykinin receptors inducing contractile responses of canine ileum circular muscle. Am J Physiol. 1995 Jan;268(1 Pt 1):G161-70. PubMed PMID: 7530911.

16: Prat A, Picard P, Couture R. Cardiovascular and behavioural effects of centrally administered neuropeptide K in the rat: receptor characterization. Br J Pharmacol. 1994 May;112(1):250-6. PubMed PMID: 7518305; PubMed Central PMCID: PMC1910298.

17: Picard P, Regoli D, Couture R. Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists. Br J Pharmacol. 1994 May;112(1):240-9. PubMed PMID: 7518304; PubMed Central PMCID: PMC1910324.

18: Robinson S, Lenfant M, Wdzieczak-Bakala J, Riches A. The molecular specificity of action of the tetrapeptide acetyl-N-Ser-Asp-Lys-Pro (AcSDKP) in the control of hematopoietic stem cell proliferation. Stem Cells. 1993 Sep;11(5):422-7. PubMed PMID: 8241953.

19: Prat A, Picard P, Regoli D, Couture R. Characterization of the cardiovascular and behavioral effects of centrally administered neuropeptide K in the conscious rat. Regul Pept. 1993 Jul 2;46(1-2):317-20. PubMed PMID: 8210496.

20: Couture R, Boucher S, Picard P, Regoli D. Receptor characterization of the spinal action of neurokinins on nociception: a three receptor hypothesis. Regul Pept. 1993 Jul 2;46(1-2):426-9. PubMed PMID: 7692557.