TSI-01
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562956

CAS#: 704878-75-1

Description: TSI-01 is a selective inhibitor of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2 (LPCAT2).

Chemical Structure

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TSI-01
CAS# 704878-75-1
Instruction

Theoretical Analysis

MedKoo Cat#: 562956
Name: TSI-01
CAS#: 704878-75-1
Chemical Formula: C14H11Cl2NO4
Exact Mass: 327.01
Molecular Weight: 328.140
Elemental Analysis: C, 51.24; H, 3.38; Cl, 21.61; N, 4.27; O, 19.50

Price and Availability

Size Price Availability Quantity
5mg USD 360
10mg USD 600
25mg USD 1130
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Synonym: TSI-01; TSI 01; TSI01;

IUPAC/Chemical Name: 4-(3,4-Dichloro-2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-benzoic acid 1-methylethyl ester

InChi Key: LZAMLWVXUVJMPU-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H11Cl2NO4/c1-7(2)21-14(20)8-3-5-9(6-4-8)17-12(18)10(15)11(16)13(17)19/h3-7H,1-2H3

SMILES Code: O=C(OC(C)C)C1=CC=C(N2C(C(Cl)=C(Cl)C2=O)=O)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 328.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Tarui M, Shindou H, Kumagai K, Morimoto R, Harayama T, Hashidate T, Kojima H, Okabe T, Nagano T, Nagase T, Shimizu T. Selective inhibitors of a PAF biosynthetic enzyme lysophosphatidylcholine acyltransferase 2. J Lipid Res. 2014 Jul;55(7):1386-96. doi: 10.1194/jlr.M049205. Epub 2014 May 21. PubMed PMID: 24850807; PubMed Central PMCID: PMC4076079.