Pseudobactin A

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596735

CAS#: 79438-64-5

Description: Pseudobactin A is a nonfluorescent extracellular siderophore produced by plant growth promoting bacterium Pseudomonas B10.

Chemical Structure

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Pseudobactin A
CAS# 79438-64-5
Instruction

Theoretical Analysis

MedKoo Cat#: 596735
Name: Pseudobactin A
CAS#: 79438-64-5
Chemical Formula: C42H62N12O16
Exact Mass: 990.44
Molecular Weight: 991.020
Elemental Analysis: C, 50.90; H, 6.31; N, 16.96; O, 25.83

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Pseudobactin A;

IUPAC/Chemical Name: (7S,11R,14S,17R,18S)-7,17-diamino-1-((1S,5S)-5-(4-amino-4-oxobutanamido)-8,9-dihydroxy-2,3,5,6-tetrahydro-1H-pyrimido[1,2-a]quinolin-1-yl)-18-hydroxy-9-(((R)-1-hydroxy-2-oxopiperidin-3-yl)-L-alanyl)-11-((R)-1-hydroxyethyl)-14-methyl-1,8,10,13,16-pentaoxo-2,9,12,15-tetraazanonadecan-19-oic acid

InChi Key: DKRKCXQSIKKJRX-HNAVCKOCSA-N

InChi Code: InChI=1S/C42H62N12O16/c1-18(49-37(63)31(45)33(60)42(68)69)35(61)51-32(20(3)55)41(67)54(38(64)19(2)48-23-8-6-14-52(70)40(23)66)39(65)22(43)7-4-5-12-47-36(62)25-11-13-46-34-24(50-30(59)10-9-29(44)58)15-21-16-27(56)28(57)17-26(21)53(25)34/h16-20,22-25,31-33,48,55-57,60,70H,4-15,43,45H2,1-3H3,(H2,44,58)(H,47,62)(H,49,63)(H,50,59)(H,51,61)(H,68,69)/t18-,19-,20+,22-,23+,24-,25-,31+,32+,33-/m0/s1

SMILES Code: ON(CCC1)C([C@@H]1N[C@@H](C)C(N(C([C@H](CCCCNC([C@@H]2CCN=C3N2c4c(C[C@@H]3NC(CCC(N)=O)=O)cc(O)c(O)c4)=O)N)=O)C([C@@H]([C@H](O)C)NC([C@H](C)NC([C@@H]([C@H](O)C(O)=O)N)=O)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 991.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Marek-Kozaczuk M, Kopcińska J, Lotocka B, Golinowski W, Skorupska A. Infection of clover by plant growth promoting Pseudomonas fluorescens strain 267 and Rhizobium leguminosarum bv. trifolii studied by mTn5-gusA. Antonie Van Leeuwenhoek. 2000 Jul;78(1):1-11. PubMed PMID: 11016690.

2: Taraz K, Seinsche D, Budzikiewicz H. [Pseudobactin and pseudobactin A variants: new pyoverdin type peptide siderophores from Pseudomonas fluorescens "E2"]. Z Naturforsch C. 1991 Jul-Aug;46(7-8):522-6. German. PubMed PMID: 1776994.

3: Magazin MD, Moores JC, Leong J. Cloning of the gene coding for the outer membrane receptor protein for ferric pseudobactin, a siderophore from a plant growth-promoting Pseudomonas strain. J Biol Chem. 1986 Jan 15;261(2):795-9. PubMed PMID: 3001083.

4: Moores JC, Magazin M, Ditta GS, Leong J. Cloning of genes involved in the biosynthesis of pseudobactin, a high-affinity iron transport agent of a plant growth-promoting Pseudomonas strain. J Bacteriol. 1984 Jan;157(1):53-8. PubMed PMID: 6690426; PubMed Central PMCID: PMC215128.

5: Teintze M, Leong J. Structure of pseudobactin A, a second siderophore from plant growth promoting Pseudomonas B10. Biochemistry. 1981 Oct 27;20(22):6457-62. PubMed PMID: 7306519.

6: Teintze M, Hossain MB, Barnes CL, Leong J, van der Helm D. Structure of ferric pseudobactin, a siderophore from a plant growth promoting Pseudomonas. Biochemistry. 1981 Oct 27;20(22):6446-57. PubMed PMID: 7306518.