WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596726
Description: L-Acosamine nucleoside is a bioactive chemical with antiviral activity against HIV and HSV-1.
MedKoo Cat#: 596726
Name: L-Acosamine nucleoside
Chemical Formula: C21H21N3O7
Exact Mass: 427.138
Molecular Weight: 427.41
Elemental Analysis: C, 59.01; H, 4.95; N, 9.83; O, 26.20
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: L-Acosamine nucleoside;
IUPAC/Chemical Name: (S)-1-((2R,3R,5R)-3-(1,3-dioxoisoindolin-2-yl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)ethyl acetate
InChi Key: GJKVGHBACKLCOR-QYHDQYMBSA-N
InChi Code: 1S/C21H21N3O7/c1-10-9-23(21(29)22-18(10)26)16-8-15(17(31-16)11(2)30-12(3)25)24-19(27)13-6-4-5-7-14(13)20(24)28/h4-7,9,11,15-17H,8H2,1-3H3,(H,22,26,29)/t11-,15+,16+,17-/m0/s1
SMILES Code: Cc(cn([C@H]1C[C@@H](N2C(c3c(C2=O)cccc3)=O)[C@H]([C@@H](OC(C)=O)C)O1)c(=O)[nH]4)c4=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 427.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Lau J, Pedersen EB, Nielsen CM. Synthesis and evaluation of antiviral activity of L-acosamine and L-ristosamine nucleosides of furanose configuration. Acta Chem Scand. 1991 Jul;45(6):616-20. PubMed PMID: 1662527.