L 671776

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596627

CAS#: 134313-74-9

Description: L 671776 is an inositol monophosphatase inhibitor isolated from Memnoniella echinata.

Chemical Structure

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L 671776
CAS# 134313-74-9
Instruction

Theoretical Analysis

MedKoo Cat#: 596627
Name: L 671776
CAS#: 134313-74-9
Chemical Formula: C23H32O5
Exact Mass: 388.23
Molecular Weight: 388.500
Elemental Analysis: C, 71.11; H, 8.30; O, 20.59

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: L 671776; L-671776; L671776; L-671,776; L 671,776; L671,776; ATCC 20928 factor B;

IUPAC/Chemical Name: 4,6'-dihydroxy-6-(hydroxymethyl)-2',5',5',8a'-tetramethyl-3',4',4a',5',6',7',8',8a'-octahydro-2'H,3H-spiro[benzofuran-2,1'-naphthalene]-5-carbaldehyde

InChi Key: HSIIEJMIARCGAU-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H32O5/c1-13-5-6-18-21(2,3)19(26)7-8-22(18,4)23(13)10-15-17(28-23)9-14(11-24)16(12-25)20(15)27/h9,12-13,18-19,24,26-27H,5-8,10-11H2,1-4H3

SMILES Code: O=CC1=C(CO)C=C(OC2(C(C)CCC3C(C)(C)C(O)CCC32C)C4)C4=C1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 388.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Stefanelli S, Sponga F, Ferrari P, Sottani C, Corti E, Brunati C, Islam K. Inhibitors of myo-inositol monophosphatase, ATCC 20928 factors A and C. Isolation, physico-chemical characterization and biological properties. J Antibiot (Tokyo). 1996 Jul;49(7):611-6. PubMed PMID: 8784418.

2: Lam YK, Wichmann CF, Meinz MS, Guariglia L, Giacobbe RA, Mochales S, Kong L, Honeycutt SS, Zink D, Bills GF, et al. A novel inositol mono-phosphatase inhibitor from Memnoniella echinata. Producing organism, fermentation, isolation, physicochemical and in vitro biological properties. J Antibiot (Tokyo). 1992 Sep;45(9):1397-403. PubMed PMID: 1331013.