L 656575

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596601

CAS#: 106036-65-1

Description: L 656575 is an oxacephem.

Chemical Structure

img
L 656575
CAS# 106036-65-1
Instruction

Theoretical Analysis

MedKoo Cat#: 596601
Name: L 656575
CAS#: 106036-65-1
Chemical Formula: C24H26N6O8S2
Exact Mass: 590.13
Molecular Weight: 590.620
Elemental Analysis: C, 48.81; H, 4.44; N, 14.23; O, 21.67; S, 10.86

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: L 656575; L-656575; L656575; L-656,575; L 656,575; L656,575; Ocp 9-176;

IUPAC/Chemical Name: (4R,6S,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-4-methyl-3-(((1-methylpyridin-1-ium-4-yl)thio)methyl)-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

InChi Key: AXPAGQFNDQXHIX-OGJJTABJSA-N

InChi Code: InChI=1S/C24H26N6O8S2/c1-11-13(9-39-12-5-7-29(4)8-6-12)17(21(33)34)30-19(32)16(20(30)37-11)27-18(31)15(14-10-40-23(25)26-14)28-38-24(2,3)22(35)36/h5-8,10-11,16,20H,9H2,1-4H3,(H4-,25,26,27,31,33,34,35,36)/b28-15-/t11-,16+,20+/m1/s1

SMILES Code: C[N+]1=CC=C(SCC([C@@H](C)O[C@@]2([H])[C@H]3NC(/C(C4=CSC(N)=N4)=N\OC(C)(C(O)=O)C)=O)=C(C([O-])=O)N2C3=O)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 590.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Hakimelahi GH, Tsay SC, Tso HH, Ramezani Z, Hwu JR. Synthesis and biological evaluation of an electronically activated isooxacephem. Bioorg Med Chem. 1996 Aug;4(8):1361-4. PubMed PMID: 8879559.

2: Gu JW, Chin NX, Neu HC. In vitro activity of an oxycephem OCP 9-176 compared with its sulfur analog and other beta-lactams. Diagn Microbiol Infect Dis. 1991 Mar-Apr;14(2):135-40. PubMed PMID: 1873972.

3: Okonogi T, Shibahara S, Murai Y, Yoshida T, Inouye S, Kondo S, Christensen BG. Synthesis and antibacterial activity of novel 2-methyl-1-oxacephalosporins. J Antibiot (Tokyo). 1990 Apr;43(4):357-71. PubMed PMID: 2351611.

4: Shibahara S, Okonogi T, Murai Y, Kudo T, Yoshida T, Kondo S, Christensen BG. Synthesis of a novel 2 beta-methyl-1-oxacephalosporin, OCP-9-176. J Antibiot (Tokyo). 1988 Aug;41(8):1154-7. PubMed PMID: 3170350.

5: Weissberger B, Abruzzo GK, Fromtling RA, Valiant ME, Shungu DL, Gadebusch HH. L-656,575 (OCP-9-176): a novel oxacephem. In vitro activity against aerobic and anaerobic clinical bacterial isolates. J Antibiot (Tokyo). 1988 Aug;41(8):1130-6. PubMed PMID: 3170346.

6: Gilfillan EC, Pelak BA, Fromtling RA, Bland J, Hadley S, Gadebusch HH. L-656,575 (OCP-9-176): a novel oxacephem. Pharmacokinetics and experimental chemotherapy. J Antibiot (Tokyo). 1988 Aug;41(8):1137-41. PubMed PMID: 3049491.