WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596532
Description: L 366811 is a potent oxytocin antagonist.
MedKoo Cat#: 596532
Name: L 366811
Chemical Formula: C43H56N8O6
Exact Mass: 780.4323
Molecular Weight: 780.97
Elemental Analysis: C, 66.13; H, 7.23; N, 14.35; O, 12.29
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Synonym: L 366811; L-366811; L366811; L-366,811; L 366,811; L366,811;
IUPAC/Chemical Name: (S)-N-((R)-1-(1H-indol-3-yl)-3-oxopropan-2-yl)-N-(L-isoleucyl)-1-((R)-3-((R)-6-(1,2-dihydropyridine-1-carbonyl)-6-(piperazine-1-carbonyl)cyclohexa-1,3-dien-1-yl)-2-(methylamino)propanoyl)pyrrolidine-2-carboxamide
InChi Key: PQTORSHXODXZHK-FZOIMTHESA-N
InChi Code: 1S/C43H56N8O6/c1-4-29(2)37(44)40(55)51(32(28-52)25-30-27-47-34-15-7-6-14-33(30)34)39(54)36-16-12-22-50(36)38(53)35(45-3)26-31-13-8-9-17-43(31,41(56)48-20-10-5-11-21-48)42(57)49-23-18-46-19-24-49/h5-11,13-15,20,27-29,32,35-37,45-47H,4,12,16-19,21-26,44H2,1-3H3/t29-,32+,35+,36-,37-,43-/m0/s1
SMILES Code: CC[C@@H]([C@H](N)C(N(C([C@@H]1CCCN1C([C@H](NC)CC2=CC=CC[C@]2(C(N3CC=CC=C3)=O)C(N4CCNCC4)=O)=O)=O)[C@@H](C=O)Cc5c6ccccc6[nH]c5)=O)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 780.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Pettibone DJ, Clineschmidt BV, Lis EV, Ransom RW, Totaro JA, Young GS, Bock MG, Freidinger RM, Veber DF, Williams PD. Bradykinin agonist activity of a novel, potent oxytocin antagonist. Eur J Pharmacol. 1991 Apr 24;196(3):233-7. PubMed PMID: 1893911.