WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596530
Description: L 365209 is an oxytocin antagonist; synthetic derivative of L 156373.
MedKoo Cat#: 596530
Name: L 365209
Chemical Formula: C40H50N8O6
Exact Mass: 738.3853
Molecular Weight: 738.89
Elemental Analysis: C, 65.02; H, 6.82; N, 15.17; O, 12.99
This product is not in stock, which may be available by custom synthesis.
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Synonym: L 365209; L-365209; L365209; L 365,209; L-365,209; L365,209;
IUPAC/Chemical Name: 16,24-dibenzyl-13-(sec-butyl)-25-methyl-1,7,8,13,14,16,17,18a,19,20,21,24,25,26a-tetradecahydro-2H,12H-dipyridazino[1,6-a:1',6'-d]pyrrolo[1,2-j][1,4,7,10,13,16]hexaazacyclooctadecine-6,12,15,18,23,26(6aH)-hexaone
InChi Key: IFHSSGUGRIXWQU-UHFFFAOYSA-N
InChi Code: InChI=1S/C40H50N8O6/c1-4-26(2)34-40(54)48-32(19-12-22-42-48)39(53)47-31(18-11-21-41-47)37(51)45(3)33(25-28-16-9-6-10-17-28)38(52)46-23-13-20-30(46)36(50)43-29(35(49)44-34)24-27-14-7-5-8-15-27/h5-10,14-17,21-22,26,29-34H,4,11-13,18-20,23-25H2,1-3H3,(H,43,50)(H,44,49)
SMILES Code: CCC(C1C(N2C(C(N3C(C(N(C)C(Cc4ccccc4)C(N5CCCC5C(NC(Cc6ccccc6)C(N1)=O)=O)=O)=O)CCC=N3)=O)CCC=N2)=O)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 738.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
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2: Williams PD, Bock MG, Tung RD, Garsky VM, Perlow DS, Erb JM, Lundell GF, Gould NP, Whitter WL, Hoffman JB, et al. Development of a novel class of cyclic hexapeptide oxytocin antagonists based on a natural product. J Med Chem. 1992 Oct 16;35(21):3905-18. PubMed PMID: 1331448.
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