Otenzepad
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MedKoo CAT#: 591289

CAS#: 102394-31-0

Description: Otenzepad, also known as AF-DX 116, is a selective M2 antagonist. Oral AF-DX 116 resulted in greater elevation of DBP than SBP in unstressed rats. In stressed rats, greater and more prolonged elevation of SBP than in unstressed rats was noted, particularly at higher doses. he effects of AF-DX 116 on blood pressure and heart rate thus may arise from peripheral action and AF-DX 116 may be useful for treating hypotension related to autonomic imbalance of the vagotonia type.


Chemical Structure

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Otenzepad
CAS# 102394-31-0

Theoretical Analysis

MedKoo Cat#: 591289
Name: Otenzepad
CAS#: 102394-31-0
Chemical Formula: C24H31N5O2
Exact Mass: 421.2478
Molecular Weight: 421.55
Elemental Analysis: C, 68.38; H, 7.41; N, 16.61; O, 7.59

Price and Availability

Size Price Availability Quantity
25.0mg USD 750.0 2 Weeks
50.0mg USD 1250.0 2 Weeks
100.0mg USD 2050.0 2 Weeks
200.0mg USD 3650.0 2 Weeks
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Synonym: Otenzepad; AF-DX 116; AF-DX-116; AF-DX116;

IUPAC/Chemical Name: 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 11-((2-((diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-

InChi Key: UBRKDAVQCKZSPO-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H31N5O2/c1-3-27(4-2)16-18-10-7-8-15-28(18)17-22(30)29-21-13-6-5-11-19(21)24(31)26-20-12-9-14-25-23(20)29/h5-6,9,11-14,18H,3-4,7-8,10,15-17H2,1-2H3,(H,26,31)

SMILES Code: O=C[4]NC[2]=CC=CN=C@3N(C(CN[20]C(CN(CC)CC)CCCC@20)=O)C[6]=CC=CC=C(@5)@7

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 421.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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