WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562882
Description: 50F10 is a stabilizer of the active LPL dimer. It acts by preventing both angptl4- and heat-induced inactivation of LPL and reducing postprandial triglyceride levels.
MedKoo Cat#: 562882
Chemical Formula: C28H25N3O5
Exact Mass: 483.1794
Molecular Weight: 483.52
Elemental Analysis: C, 69.55; H, 5.21; N, 8.69; O, 16.54
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: 50F10; 50-F-10; 50 F 10;
IUPAC/Chemical Name: 2,3-Dihydro-2-[3-[[(4-methylphenyl)amino]carbonyl]-4-(1-piperidinyl)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid
InChi Key: BRZAMKDHLIXUND-UHFFFAOYSA-N
InChi Code: InChI=1S/C28H25N3O5/c1-17-5-8-19(9-6-17)29-25(32)23-16-20(10-12-24(23)30-13-3-2-4-14-30)31-26(33)21-11-7-18(28(35)36)15-22(21)27(31)34/h5-12,15-16H,2-4,13-14H2,1H3,(H,29,32)(H,35,36)
SMILES Code: O=C(C1=CC2=C(C(N(C3=CC=C(N4CCCCC4)C(C(NC5=CC=C(C)C=C5)=O)=C3)C2=O)=O)C=C1)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 483.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Larsson M, Caraballo R, Ericsson M, Lookene A, Enquist PA, Elofsson M, Nilsson SK, Olivecrona G. Identification of a small molecule that stabilizes lipoprotein lipase in vitro and lowers triglycerides in vivo. Biochem Biophys Res Commun. 2014 Jul 25;450(2):1063-9. doi: 10.1016/j.bbrc.2014.06.114. Epub 2014 Jun 28. PubMed PMID: 24984153.