Proline
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MedKoo CAT#: 596448

CAS#: 147-85-3

Description: Proline is a non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.


Chemical Structure

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Proline
CAS# 147-85-3

Theoretical Analysis

MedKoo Cat#: 596448
Name: Proline
CAS#: 147-85-3
Chemical Formula: C5H9NO2
Exact Mass: 115.06
Molecular Weight: 115.130
Elemental Analysis: C, 52.16; H, 7.88; N, 12.17; O, 27.79

Price and Availability

Size Price Availability Quantity
25g USD 350 2 Weeks
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Synonym: Proline; CB 1707; FEMA No. 3319; HSDB 1210; NSC 46703; NSC-46703; NSC46703; Prolina;

IUPAC/Chemical Name: L-proline

InChi Key: ONIBWKKTOPOVIA-BYPYZUCNSA-N

InChi Code: InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1

SMILES Code: O=C(O)[C@H]1NCCC1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 115.130000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Abdullah M, Attia FN. Vitamin, C (Ascorbic Acid). 2018 May 9. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2018 Jan-. Available from http://www.ncbi.nlm.nih.gov/books/NBK499877/ PubMed PMID: 29763052. 2: Zhu X, Bao Y, Guo Y, Yang W. Proline-Rich Protein Tyrosine Kinase 2 in Inflammation and Cancer. Cancers (Basel). 2018 May 8;10(5). pii: E139. doi: 10.3390/cancers10050139. Review. PubMed PMID: 29738483. 3: Gournas C, Athanasopoulos A, Sophianopoulou V. On the Evolution of Specificity in Members of the Yeast Amino Acid Transporter Family as Parts of Specific Metabolic Pathways. Int J Mol Sci. 2018 May 8;19(5). pii: E1398. doi: 10.3390/ijms19051398. Review. PubMed PMID: 29738448. 4: Yu X, Li W, Deng Q, Li L, Hsi ED, Young KH, Zhang M, Li Y. MYD88 L265P Mutation in Lymphoid Malignancies. Cancer Res. 2018 May 15;78(10):2457-2462. doi: 10.1158/0008-5472.CAN-18-0215. Epub 2018 Apr 27. Review. PubMed PMID: 29703722. 5: Khattab HM, Kubota S, Takigawa M, Kuboki T, Sebald W. The BMP-2 mutant L51P: a BMP receptor IA binding-deficient inhibitor of noggin. J Bone Miner Metab. 2018 Apr 17. doi: 10.1007/s00774-018-0925-0. [Epub ahead of print] Review. PubMed PMID: 29667005. 6: Dessaux Y, Faure D. Quorum Sensing and Quorum Quenching in Agrobacterium: A "Go/No Go System"? Genes (Basel). 2018 Apr 16;9(4). pii: E210. doi: 10.3390/genes9040210. Review. PubMed PMID: 29659511; PubMed Central PMCID: PMC5924552. 7: Zhao Y, Lukiw WJ. Bacteroidetes Neurotoxins and Inflammatory Neurodegeneration. Mol Neurobiol. 2018 Apr 10. doi: 10.1007/s12035-018-1015-y. [Epub ahead of print] Review. PubMed PMID: 29637444. 8: Mishra AK, Choi J, Moon E, Baek KH. Tryptophan-Rich and Proline-Rich Antimicrobial Peptides. Molecules. 2018 Apr 2;23(4). pii: E815. doi: 10.3390/molecules23040815. Review. PubMed PMID: 29614844. 9: Marzol E, Borassi C, Bringas M, Sede A, Rodríguez Garcia DR, Capece L, Estevez JM. Filling the Gaps to Solve the Extensin Puzzle. Mol Plant. 2018 May 7;11(5):645-658. doi: 10.1016/j.molp.2018.03.003. Epub 2018 Mar 10. Review. PubMed PMID: 29530817. 10: Carillo P. GABA Shunt in Durum Wheat. Front Plant Sci. 2018 Feb 2;9:100. doi: 10.3389/fpls.2018.00100. eCollection 2018. Review. PubMed PMID: 29456548; PubMed Central PMCID: PMC5801424. 11: Fritzler MJ, Hudson M, Choi MY, Mahler M, Wang M, Bentow C, Milo J, Baron M; Canadian Scleroderma Research Group. Bicaudal D2 is a novel autoantibody target in systemic sclerosis that shares a key epitope with CENP-A but has a distinct clinical phenotype. Autoimmun Rev. 2018 Mar;17(3):267-275. doi: 10.1016/j.autrev.2018.01.006. Epub 2018 Jan 31. Review. PubMed PMID: 29369808. 12: Rahimi N. Defenders and Challengers of Endothelial Barrier Function. Front Immunol. 2017 Dec 18;8:1847. doi: 10.3389/fimmu.2017.01847. eCollection 2017. Review. PubMed PMID: 29326721; PubMed Central PMCID: PMC5741615. 13: Kang HJ, Rosenwaks Z. p53 and reproduction. Fertil Steril. 2018 Jan;109(1):39-43. doi: 10.1016/j.fertnstert.2017.11.026. Review. PubMed PMID: 29307398. 14: Abbas G, Murtaza B, Bibi I, Shahid M, Niazi NK, Khan MI, Amjad M, Hussain M; Natasha. Arsenic Uptake, Toxicity, Detoxification, and Speciation in Plants: Physiological, Biochemical, and Molecular Aspects. Int J Environ Res Public Health. 2018 Jan 2;15(1). pii: E59. doi: 10.3390/ijerph15010059. Review. PubMed PMID: 29301332; PubMed Central PMCID: PMC5800158. 15: Koga R, Miyoshi Y, Sakaue H, Hamase K, Konno R. Mouse d-Amino-Acid Oxidase: Distribution and Physiological Substrates. Front Mol Biosci. 2017 Dec 4;4:82. doi: 10.3389/fmolb.2017.00082. eCollection 2017. Review. PubMed PMID: 29255714; PubMed Central PMCID: PMC5722847. 16: Schindler L, Dickerhof N, Hampton MB, Bernhagen J. Post-translational regulation of macrophage migration inhibitory factor: Basis for functional fine-tuning. Redox Biol. 2018 May;15:135-142. doi: 10.1016/j.redox.2017.11.028. Epub 2017 Dec 6. Review. PubMed PMID: 29247897. 17: Hakim, Ullah A, Hussain A, Shaban M, Khan AH, Alariqi M, Gul S, Jun Z, Lin S, Li J, Jin S, Munis MFH. Osmotin: A plant defense tool against biotic and abiotic stresses. Plant Physiol Biochem. 2018 Feb;123:149-159. doi: 10.1016/j.plaphy.2017.12.012. Epub 2017 Dec 7. Review. PubMed PMID: 29245030. 18: Urade R, Sato N, Sugiyama M. Gliadins from wheat grain: an overview, from primary structure to nanostructures of aggregates. Biophys Rev. 2018 Apr;10(2):435-443. doi: 10.1007/s12551-017-0367-2. Epub 2017 Dec 4. Review. PubMed PMID: 29204878; PubMed Central PMCID: PMC5899726. 19: Wan Q, Hongbo S, Zhaolong X, Jia L, Dayong Z, Yihong H. Salinity Tolerance Mechanism of Osmotin and Osmotin-like Proteins: A Promising Candidate for Enhancing Plant Salt Tolerance. Curr Genomics. 2017 Dec;18(6):553-556. doi: 10.2174/1389202918666170705153045. Review. PubMed PMID: 29204083; PubMed Central PMCID: PMC5684654. 20: He H, He LF. Regulation of gaseous signaling molecules on proline metabolism in plants. Plant Cell Rep. 2018 Mar;37(3):387-392. doi: 10.1007/s00299-017-2239-4. Epub 2017 Nov 25. Review. PubMed PMID: 29177845.