Nebivolol HCl

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MedKoo CAT#: 562878

CAS#: 152520-56-4

Description: Nebivolol HCl is a selective beta1-receptor antagonist.

Price and Availability

Size Price Shipping out time Quantity
10mg USD 240 2 Weeks
50mg USD 550 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-09-28. Prices are subject to change without notice.

Nebivolol HCl, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 562878
Name: Nebivolol HCl
CAS#: 152520-56-4
Chemical Formula: C22H26ClF2NO4
Exact Mass:
Molecular Weight: 441.89
Elemental Analysis: C, 59.80; H, 5.93; Cl, 8.02; F, 8.60; N, 3.17; O, 14.48

Synonym: Nebivolol HCl; Nebivolol Hydrochloride; Silostar; Bystolic, R-67145; R 67145; R67145;

IUPAC/Chemical Name: (R)-1-((R)-6-fluorochroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethan-1-ol hydrochloride


InChi Code: InChI=1S/C22H25F2NO4.ClH/c23-15-3-7-19-13(9-15)1-5-21(28-19)17(26)11-25-12-18(27)22-6-2-14-10-16(24)4-8-20(14)29-22;/h3-4,7-10,17-18,21-22,25-27H,1-2,5-6,11-12H2;1H/t17-,18+,21-,22+;

SMILES Code: O[C@@H]([C@H]1CCC2=C(O1)C=CC(F)=C2)CNC[C@H](O)[C@@H]3CCC4=C(O3)C=CC(F)=C4.[H]Cl

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Abdel-Fattah L, Abdel-Aziz L, El-Kosasy A, Gaied M. Quantification of nebivolol hydrochloride in human plasma by liquid chromatography using fluorescence detection: Use in pharmacokinetic study. Drug Discov Ther. 2010 Dec;4(6):418-22. PubMed PMID: 22491307.

2: Hussar DA. New drugs 09, part 1. Plast Surg Nurs. 2009 Oct-Dec;29(4):228-36; quiz 237-8. doi: 10.1097/PSN.0b013e3181d0512c. Review. PubMed PMID: 20029303.

3: Bundkirchen A, Brixius K, Bölck B, Nguyen Q, Schwinger RH. Beta 1-adrenoceptor selectivity of nebivolol and bisoprolol. A comparison of [3H]CGP 12.177 and [125I]iodocyanopindolol binding studies. Eur J Pharmacol. 2003 Jan 26;460(1):19-26. PubMed PMID: 12535855.