NBD-10007

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MedKoo CAT#: 562860

CAS#: 1375736-65-4

Description: NBD-10007 is a HIV-1 entry inhibitor.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-08-03. Prices are subject to change without notice.

NBD-10007 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562860
Name: NBD-10007
CAS#: 1375736-65-4
Chemical Formula: C20H25ClN4O3S
Exact Mass: 436.1336
Molecular Weight: 436.95
Elemental Analysis: C, 54.98; H, 5.77; Cl, 8.11; N, 12.82; O, 10.98; S, 7.34


Synonym: NBD-10007; NBD 10007; NBD10007;

IUPAC/Chemical Name: N1-(4-chlorophenyl)-N2-((5-(2-hydroxyethyl)-4-methylthiazol-2-yl)(piperidin-2-yl)methyl)oxalamide

InChi Key: CXKXTRRHRJSSBG-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H25ClN4O3S/c1-12-16(9-11-26)29-20(23-12)17(15-4-2-3-10-22-15)25-19(28)18(27)24-14-7-5-13(21)6-8-14/h5-8,15,17,22,26H,2-4,9-11H2,1H3,(H,24,27)(H,25,28)

SMILES Code: ClC1=CC=C(NC(C(NC(C2=NC(C)=C(CCO)S2)C3NCCCC3)=O)=O)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Curreli F, Kwon YD, Zhang H, Yang Y, Scacalossi D, Kwong PD, Debnath AK. Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study. Antimicrob Agents Chemother. 2014 Sep;58(9):5478-91. doi: 10.1128/AAC.03339-14. Epub 2014 Jul 7. PubMed PMID: 25001301; PubMed Central PMCID: PMC4135886.