WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562852
CAS#: 1619884-65-9
Description: PSB-1434 is a potent, selective, competitive, and reversible inhibitor of monoamine oxidase B (MAO-B).
MedKoo Cat#: 562852
Name: PSB-1434
CAS#: 1619884-65-9
Chemical Formula: C14H9F2N3O
Exact Mass: 273.0714
Molecular Weight: 273.24
Elemental Analysis: C, 61.54; H, 3.32; F, 13.91; N, 15.38; O, 5.86
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: PSB-1434; PSB 1434; PSB1434;
IUPAC/Chemical Name: N-(3,4-Difluorophenyl)-1H-indazole-5-carboxamide
InChi Key: SFDOMGAQGMFHNI-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H9F2N3O/c15-11-3-2-10(6-12(11)16)18-14(20)8-1-4-13-9(5-8)7-17-19-13/h1-7H,(H,17,19)(H,18,20)
SMILES Code: O=C(C1=CC2=C(NN=C2)C=C1)NC3=CC=C(F)C(F)=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 273.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Tzvetkov NT, Hinz S, Küppers P, Gastreich M, Müller CE. Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency. J Med Chem. 2014 Aug 14;57(15):6679-703. doi: 10.1021/jm500729a. Epub 2014 Jul 16. PubMed PMID: 24955776.
