Naratriptan HCl
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MedKoo CAT#: 562847

CAS#: 143388-64-1

Description: Naratriptan HCl is a 5-hydroxytryptamine-1 (5-HT1) receptor subtype agonist.


Price and Availability

Size Price Shipping out time Quantity
5mg USD 210 2 Weeks
10mg USD 340 2 Weeks
25mg USD 570 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-09. Prices are subject to change without notice.

Naratriptan HCl, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 562847
Name: Naratriptan HCl
CAS#: 143388-64-1
Chemical Formula: C17H26ClN3O2S
Exact Mass: 371.1434
Molecular Weight: 371.92
Elemental Analysis: C, 54.90; H, 7.05; Cl, 9.53; N, 11.30; O, 8.60; S, 8.62


Synonym: Naratriptan HCl; Naratriptan Hydrochloride; Amerge; Naramig; GR-85548A; GR 85548A; GR85548A;

IUPAC/Chemical Name: N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide hydrochloride

InChi Key: AWEZYKMQFAUBTD-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H

SMILES Code: CN1CCC(C2=CNC3=C2C=C(CCS(=O)(NC)=O)C=C3)CC1.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Sattar M, Lane ME. Oral transmucosal delivery of naratriptan. Int J Pharm. 2016 Nov 30;514(1):263-269. doi: 10.1016/j.ijpharm.2016.06.039. PubMed PMID: 27863671.

2: Prajapati PB, Chotalia J, Bodiwala KB, Marolia BP, Shah SA. Development and Validation of Stability-Indicating HPTLC Method for Estimation of Naratriptan Hydrochloride in Its Pharmaceutical Dosage Form and Its Content Uniformity Testing. J Chromatogr Sci. 2016 Aug;54(7):1129-36. doi: 10.1093/chromsci/bmw080. PubMed PMID: 27406125.

3: Sattar M, Hadgraft J, Lane ME. Preparation, characterization and buccal permeation of naratriptan. Int J Pharm. 2015 Sep 30;493(1-2):146-51. doi: 10.1016/j.ijpharm.2015.07.035. Epub 2015 Jul 18. PubMed PMID: 26196276.