L 12407

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596386

CAS#: 35175-14-5

Description: L 12407 is an antiprotozoal drug of the nitroimidazole class used in veterinary medicine. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.

Chemical Structure

L 12407
CAS# 35175-14-5

Theoretical Analysis

MedKoo Cat#: 596386
Name: L 12407
CAS#: 35175-14-5
Chemical Formula: C7H11N3O3
Exact Mass: 185.08
Molecular Weight: 185.183
Elemental Analysis: C, 45.40; H, 5.99; N, 22.69; O, 25.92

Price and Availability

Size Price Availability Quantity
10mg USD 350 2 Weeks
100mg USD 1150 2 Weeks
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Synonym: L 12407; L-12407; L12407; Ipronidazole-OH;

IUPAC/Chemical Name: 2-(1-methyl-5-nitro-1H-imidazol-2-yl)propan-2-ol


InChi Code: InChI=1S/C7H11N3O3/c1-7(2,11)6-8-4-5(9(6)3)10(12)13/h4,11H,1-3H3

SMILES Code: OC(C)(C)C1=NC=C([N+]([O-])=O)N1C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Biological target: Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ).
In vitro activity: TBD
In vivo activity: TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 185.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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1: Lin Z, Zhen Z, Chen C, Li Y, Luo C, Zhong L, Hu H, Li J, Zhang Y, Liang Y, Yang J, Zhang D. Rhizospheric effects on atrazine speciation and degradation in laterite soils of Pennisetum alopecuroides (L.) Spreng. Environ Sci Pollut Res Int. 2018 May;25(13):12407-12418. doi: 10.1007/s11356-018-1468-6. Epub 2018 Feb 19. PubMed PMID: 29460244.

2: Chen J, Qian Y, Li H, Cheng Y, Zhao M. The reduced bioavailability of copper by nano-TiO₂ attenuates the toxicity to Microcystis aeruginosa. Environ Sci Pollut Res Int. 2015 Aug;22(16):12407-14. doi: 10.1007/s11356-015-4492-9. Epub 2015 Apr 23. PubMed PMID: 25903177.

3: Das LK, Kadam RM, Bauzá A, Frontera A, Ghosh A. Differences in nuclearity, molecular shapes, and coordination modes of azide in the complexes of Cd(II) and Hg(II) with a "metalloligand" [CuL] (H2L = N,N'-bis(salicylidene)-1,3-propanediamine): characterization in solid and in solutions, and theoretical calculations. Inorg Chem. 2012 Nov 19;51(22):12407-18. doi: 10.1021/ic301773h. Epub 2012 Nov 6. PubMed PMID: 23131113.

4: Klein RR, Bourdon DM, Costales CL, Wagner CD, White WL, Williams JD, Hicks SN, Sondek J, Thakker DR. Direct activation of human phospholipase C by its well known inhibitor u73122. J Biol Chem. 2011 Apr 8;286(14):12407-16. doi: 10.1074/jbc.M110.191783. Epub 2011 Jan 25. PubMed PMID: 21266572; PubMed Central PMCID: PMC3069444.