Pyrvinium chloride

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MedKoo CAT#: 562838

CAS#: 548-84-5 (Cl)

Description: Pyrvinium (Viprynium) is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinium was identified as a potent Wnt inhibitor, acting through activation of Casein kinase CK1α. Pyrvinium salts can also inhibit the growth of cancer cells.[6] More specifically, the pamoate salt has been shown to have preferential toxicity for various cancer cell lines during glucose starvation.

Chemical Structure

Pyrvinium chloride
CAS# 548-84-5 (Cl)

Theoretical Analysis

MedKoo Cat#: 562838
Name: Pyrvinium chloride
CAS#: 548-84-5 (Cl)
Chemical Formula: C26H28ClN
Exact Mass:
Molecular Weight: 417.98
Elemental Analysis: C, 74.71; H, 6.75; Cl, 8.48; N, 10.05

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 110-85-0 (cation)   142-88-1 (adipate)   3546-41-6 (pamoate); 548-84-5 (Cl)   35648-29-4 (Iodide)    

Synonym: Pyrvinium chloride; Vipyrvinium embonate, Altolat, Alnoxin, Pamovin, Vermitibier; NSC 223622; NSC223622; NSC-223622; VPC-14337; VPC 14337; VPC14337;

IUPAC/Chemical Name: (E)-2-(2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)vinyl)-6-(dimethylamino)-1-methylquinolin-1-ium chloride


InChi Code: InChI=1S/C26H28N3.ClH/c1-19-17-21(20(2)29(19)24-9-7-6-8-10-24)11-13-23-14-12-22-18-25(27(3)4)15-16-26(22)28(23)5;/h6-18H,1-5H3;1H/q+1;/p-1

SMILES Code: CN(C1=CC2=C(C=C1)[N+](C)=C(C=C2)/C=C/C3=C(N(C(C)=C3)C4=CC=CC=C4)C)C.[Cl-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 417.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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