WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562838
CAS#: 548-84-5 (Cl)
Description: Pyrvinium (Viprynium) is an anthelmintic effective for pinworms. Several forms of pyrvinium have been prepared with variable counter anions, such as halides, tosylate, triflate and pamoate. Pyrvinium was identified as a potent Wnt inhibitor, acting through activation of Casein kinase CK1α. Pyrvinium salts can also inhibit the growth of cancer cells.[6] More specifically, the pamoate salt has been shown to have preferential toxicity for various cancer cell lines during glucose starvation.
MedKoo Cat#: 562838
Name: Pyrvinium chloride
CAS#: 548-84-5 (Cl)
Chemical Formula: C26H28ClN
Exact Mass:
Molecular Weight: 417.98
Elemental Analysis: C, 74.71; H, 6.75; Cl, 8.48; N, 10.05
This product is not in stock, which may be available by custom synthesis.
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Related CAS #: 110-85-0 (cation) 142-88-1 (adipate) 3546-41-6 (pamoate); 548-84-5 (Cl) 35648-29-4 (Iodide)
Synonym: Pyrvinium chloride; Vipyrvinium embonate, Altolat, Alnoxin, Pamovin, Vermitibier; NSC 223622; NSC223622; NSC-223622; VPC-14337; VPC 14337; VPC14337;
IUPAC/Chemical Name: (E)-2-(2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)vinyl)-6-(dimethylamino)-1-methylquinolin-1-ium chloride
InChi Key: IKUGNXPCGVYRHO-UHFFFAOYSA-M
InChi Code: InChI=1S/C26H28N3.ClH/c1-19-17-21(20(2)29(19)24-9-7-6-8-10-24)11-13-23-14-12-22-18-25(27(3)4)15-16-26(22)28(23)5;/h6-18H,1-5H3;1H/q+1;/p-1
SMILES Code: CN(C1=CC2=C(C=C1)[N+](C)=C(C=C2)/C=C/C3=C(N(C(C)=C3)C4=CC=CC=C4)C)C.[Cl-]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 417.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
