Piperazine adipate

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MedKoo CAT#: 591174

CAS#: 142-88-1 (adipate)

Description: Piperazine is biochemical, which may be an alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). Piperazine is especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine blocks the response of the worm muscle (best studied in Ascaris ) to acetylcholine, presumably by causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.

Chemical Structure

Piperazine adipate
CAS# 142-88-1 (adipate)

Theoretical Analysis

MedKoo Cat#: 591174
Name: Piperazine adipate
CAS#: 142-88-1 (adipate)
Chemical Formula: C10H20N2O4
Exact Mass: 232.1423
Molecular Weight: 232.28
Elemental Analysis: C, 51.71; H, 8.68; N, 12.06; O, 27.55

Price and Availability

Size Price Availability Quantity
25.0g USD 350.0 2 Weeks
100.0g USD 950.0 2 Weeks
500.0g USD 1450.0 2 Weeks
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Related CAS #: 110-85-0 (free base)   142-88-1 (adipate)   3546-41-6 (pamoate); 548-84-5 (Cl); 35648-29-4 (Iodide)  

Synonym: Piperazine adipate; NSC 74383; NSC-74383; NSC74383;

IUPAC/Chemical Name: Hexanedioic acid, compd. with piperazine (1:1)


InChi Code: InChI=1S/C6H10O4.C4H10N2/c7-5(8)3-1-2-4-6(9)10;1-2-6-4-3-5-1/h1-4H2,(H,7,8)(H,9,10);5-6H,1-4H2


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 232.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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20: Kühn W, Buchwalder R, Gräfner G, Hiepe T. [Control of ascriasis in the domestic fowl by use of piperazine adipate--with special reference to laying performance]. Monatsh Veterinarmed. 1971 Jul;26(14):540-2. German. PubMed PMID: 5113708.