WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 591174
CAS#: 142-88-1 (adipate)
Description: Piperazine is biochemical, which may be an alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). Piperazine is especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine blocks the response of the worm muscle (best studied in Ascaris ) to acetylcholine, presumably by causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.
MedKoo Cat#: 591174
Name: Piperazine adipate
CAS#: 142-88-1 (adipate)
Chemical Formula: C10H20N2O4
Exact Mass: 232.1423
Molecular Weight: 232.28
Elemental Analysis: C, 51.71; H, 8.68; N, 12.06; O, 27.55
Related CAS #: 110-85-0 (free base) 142-88-1 (adipate) 3546-41-6 (pamoate); 548-84-5 (Cl); 35648-29-4 (Iodide)
Synonym: Piperazine adipate; NSC 74383; NSC-74383; NSC74383;
IUPAC/Chemical Name: Hexanedioic acid, compd. with piperazine (1:1)
InChi Key: BVEGEKOBSPXUJS-UHFFFAOYSA-N
InChi Code: InChI=1S/C6H10O4.C4H10N2/c7-5(8)3-1-2-4-6(9)10;1-2-6-4-3-5-1/h1-4H2,(H,7,8)(H,9,10);5-6H,1-4H2
SMILES Code: O=C(O)CCCCC(O)=O.N1CCNCC1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 232.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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