o-Iodohippurate sodium
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596260

CAS#: 133-17-5 (sodium)

Description: o-Iodohippurate sodium is an analogue of p-aminohippuric acid for the determination of effective renal plasma flow. Labelled OIH has a significantly higher clearance than other radiopharmaceutical yet developed and is eminently suitable for renography. It is eliminated mainly by tubular secretion. In patients with normally functioning kidneys, 85% of the OIH may be found in the urine 30 minutes after intravenous injection.


Chemical Structure

img
o-Iodohippurate sodium
CAS# 133-17-5 (sodium)

Theoretical Analysis

MedKoo Cat#: 596260
Name: o-Iodohippurate sodium
CAS#: 133-17-5 (sodium)
Chemical Formula: C9H7INNaO3
Exact Mass:
Molecular Weight: 327.05
Elemental Analysis: C, 33.05; H, 2.16; I, 38.80; N, 4.28; Na, 7.03; O, 14.68

Price and Availability

Size Price Availability Quantity
15.0mg USD 350.0 2 Weeks
Bulk inquiry

Related CAS #: 5990-94-3 (sodium hydrate)   133-17-5 (sodium)    

Synonym: o-Iodohippurate sodium; Hippodin; Sodium iodohippurate NSC 63351; NSC-63351; NSC63351;

IUPAC/Chemical Name: sodium (2-iodobenzoyl)glycinate

InChi Key: XYITYKDGJLHYPW-UHFFFAOYSA-M

InChi Code: InChI=1S/C9H8INO3.Na/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13;/h1-4H,5H2,(H,11,14)(H,12,13);/q;+1/p-1

SMILES Code: O=C([O-])CNC(C1=CC=CC=C1I)=O.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 327.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Mukai T, Fujioka Y, Arano Y, Saji H. [Design of radiolabeled antibody fragments for tumor-selective radioactivity localization--brush border enzyme-sensitive bond to decrease renal accumulation of radioactivity]. Yakugaku Zasshi. 2003 Aug;123(8):647-52. Review. Japanese. PubMed PMID: 12931660.

2: Fine EJ. Interventions in renal scintirenography. Semin Nucl Med. 1999 Apr;29(2):128-45. Review. PubMed PMID: 10321825.

3: Taylor A. Radionuclide renography: a personal approach. Semin Nucl Med. 1999 Apr;29(2):102-27. Review. PubMed PMID: 10321824.

4: el Maghraby TA, van Eck-Smit BL, de Fijter JW, Pauwels EK. Quantitative scintigraphic parameters for the assessment of renal transplant patients. Eur J Radiol. 1998 Oct;28(3):256-69. Review. PubMed PMID: 9881262.

5: Roarke MC, Sandler CM. Provocative imaging. Diuretic renography. Urol Clin North Am. 1998 May;25(2):227-49. Review. PubMed PMID: 9633578.

6: Nagai T. [The measurement of renal plasma flow]. Nihon Rinsho. 1997 Apr;55 Suppl 2:597-600. Review. Japanese. PubMed PMID: 9172599.

7: Piepenburg R, Melchior SW, Steinert H, Hohenfellner R, Hahn K. [Quantitative nuclear medicine kidney diagnosis with kidney tubule traversing radioisotopes]. Urologe A. 1993 Mar;32(2):81-93. Review. German. PubMed PMID: 8475615.

8: Sanger JJ, Kramer EL. Radionuclide quantitation of renal function. Urol Radiol. 1992;14(2):69-78. Review. PubMed PMID: 1509629.

9: Blaufox MD, Dubovsky EV, Hilson AJ, Taylor A Jr, de Zeeuw R. Report of the Working Party Group on Determining the Radionuclide of Choice. Am J Hypertens. 1991 Dec;4(12 Pt 2):747S-748S. Review. PubMed PMID: 1777190.

10: Oei HY. Captopril renography. Early observations and diagnostic criteria. Am J Hypertens. 1991 Dec;4(12 Pt 2):678S-684S. Review. PubMed PMID: 1837990.

11: Abdel-Dayem HM, Turoglu HT. Radionuclide renal studies. Curr Opin Radiol. 1990 Dec;2(6):834-43. Review. PubMed PMID: 2149277.

12: Kowalczyk M. [Possibility of quantitative evaluation of renal function based on the renography alone]. Folia Med Cracov. 1989;30(1-2):45-61. Review. Polish. PubMed PMID: 2701819.

13: Dubovsky EV, Russell CD. Radionuclide evaluation of renal transplants. Semin Nucl Med. 1988 Jul;18(3):181-98. Review. PubMed PMID: 2972068.

14: Velchik MG. Radionuclide imaging of the urinary tract. Urol Clin North Am. 1985 Nov;12(4):603-31. Review. PubMed PMID: 2997967.

15: Mandell VS, Mandell J, Gaisie G. Pediatric urologic radiology. Intervention and endourology. Urol Clin North Am. 1985 Feb;12(1):151-68. Review. PubMed PMID: 2983473.

16: Dubovsky EV, Russell CD. Quantitation of renal function with glomerular and tubular agents. Semin Nucl Med. 1982 Oct;12(4):308-29. Review. PubMed PMID: 6760399.

17: Sherman RA, Byun KJ. Nuclear medicine in acute and chronic renal failure. Semin Nucl Med. 1982 Jul;12(3):265-79. Review. PubMed PMID: 6289457.

18: Chervu LR, Blaufox MD. Renal radiopharmaceuticals--an update. Semin Nucl Med. 1982 Jul;12(3):224-45. Review. PubMed PMID: 6289454.

19: Vetter W, Vetter H, Kuhlmann U, Grüntzig A, Pouliadis G, Meier W, Largiadèr F, Studer A, Siebenschein R, Furrer J, Tenschert W, Siegenthaler W. [Clinical picture, diagnosis and therapy of renovascular hypertension]. Schweiz Med Wochenschr. 1979 Mar 17;109(11):384-94. Review. German. PubMed PMID: 370974.

20: Balogh F, Szomor L. A survey of radioisotope methods used in urological diagnostics. Int Urol Nephrol. 1977;9(3):199-211. Review. PubMed PMID: 344253.