WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 341592
CAS#: 71547-95-0
Description: We 1008 is a biochemical.
MedKoo Cat#: 341592
Name: We 1008
CAS#: 71547-95-0
Chemical Formula: C19H16BrClN4OS
Exact Mass: 461.9917
Molecular Weight: 463.778
Elemental Analysis: C, 49.21; H, 3.48; Br, 17.23; Cl, 7.64; N, 12.08; O, 3.45; S, 6.91
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: We 1008; We -; We1008.
IUPAC/Chemical Name: 8-Bromo-6-(ortho-chlorophenyl)-1-tetrahydro-4-pyranyl-4H-5-triazolo(3,4-c)thieno(2,3-e)-1,4-diazepine
InChi Key: GALDCNVZNXARAF-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H16BrClN4OS/c20-15-9-13-17(12-3-1-2-4-14(12)21)22-10-16-23-24-18(25(16)19(13)27-15)11-5-7-26-8-6-11/h1-4,9,11H,5-8,10H2
SMILES Code: c1ccc(c(c1)C2=NCc3nnc(n3-c4c2cc(s4)Br)C5CCOCC5)Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 463.778 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Ikeda M, Weber KH, Bechtel WD, Malatynska E, Yamamura HI. Relative efficacies of 1,4-diazepines on GABA-stimulated chloride influx in rat brain vesicles. Life Sci. 1989;45(4):349-58. PubMed PMID: 2569655.
2: Weber KH, Kuhn FJ, Böke-Kuhn K, Lehr E, Danneberg PB, Hommer D, Paul SM, Skolnick P. Pharmacological and neurochemical properties of 1,4-diazepines with two annelated heterocycles ('hetrazepines'). Eur J Pharmacol. 1985 Feb 12;109(1):19-31. PubMed PMID: 2986988.
