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MedKoo CAT#: 562749

CAS#: 17392-79-9

Description: NSC114792 is a selective inhibitor of JAK3.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-08-03. Prices are subject to change without notice.

NSC114792 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 562749
Name: NSC114792
CAS#: 17392-79-9
Chemical Formula: C26H32N4O2S
Exact Mass: 464.2246
Molecular Weight: 464.62
Elemental Analysis: C, 67.21; H, 6.94; N, 12.06; O, 6.89; S, 6.90

Synonym: NSC114792; NSC-114792; NSC 114792;

IUPAC/Chemical Name: 21-(6-Mercapto-9H-purin-9-yl)pregn-4-ene-3,20-dione


InChi Code: InChI=1S/C26H32N4O2S/c1-25-9-7-16(31)11-15(25)3-4-17-18-5-6-20(26(18,2)10-8-19(17)25)21(32)12-30-14-29-22-23(30)27-13-28-24(22)33/h11,13-14,17-20H,3-10,12H2,1-2H3,(H,27,28,33)/t17-,18-,19-,20+,25-,26-/m0/s1

SMILES Code: C[C@@]12[C@@H](C(CN3C=NC4=C(S)N=CN=C34)=O)CC[C@@]1([H])[C@]5([H])CCC6=CC(CC[C@]6(C)[C@@]5([H])CC2)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Kim BH, Jee JG, Yin CH, Sandoval C, Jayabose S, Kitamura D, Bach EA, Baeg GH. NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3. Mol Cancer. 2010 Feb 11;9:36. doi: 10.1186/1476-4598-9-36. PubMed PMID: 20149240; PubMed Central PMCID: PMC2830973.