WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562738
Description: Mycro3 is an inhibitor of Myc-Max dimerization.
MedKoo Cat#: 562738
Chemical Formula: C24H17ClF2N6O4
Exact Mass: 526.0968
Molecular Weight: 526.88
Elemental Analysis: C, 54.71; H, 3.25; Cl, 6.73; F, 7.21; N, 15.95; O, 12.15
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Mycro3; Mycro-3; Mycro 3;
IUPAC/Chemical Name: 5-[[[7-(Chlorodifluoromethyl)-5-(2-furanyl)pyrazolo[1,5-a]pyrimidin-2-yl]carbonyl]amino]-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester
InChi Key: YPPNLSKYXDXQGD-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H17ClF2N6O4/c1-2-36-23(35)15-13-28-32(14-7-4-3-5-8-14)21(15)30-22(34)17-12-20-29-16(18-9-6-10-37-18)11-19(24(25,26)27)33(20)31-17/h3-13H,2H2,1H3,(H,30,34)
SMILES Code: O=C(C1=C(NC(C2=NN3C(C(F)(Cl)F)=CC(C4=CC=CO4)=NC3=C2)=O)N(C5=CC=CC=C5)N=C1)OCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 526.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Stellas D, Szabolcs M, Koul S, Li Z, Polyzos A, Anagnostopoulos C, Cournia Z, Tamvakopoulos C, Klinakis A, Efstratiadis A. Therapeutic effects of an anti-Myc drug on mouse pancreatic cancer. J Natl Cancer Inst. 2014 Oct 11;106(12). pii: dju320. doi: 10.1093/jnci/dju320. Print 2014 Dec. PubMed PMID: 25306215.
2: Bonham AJ, Wenta N, Osslund LM, Prussin AJ 2nd, Vinkemeier U, Reich NO. STAT1:DNA sequence-dependent binding modulation by phosphorylation, protein:protein interactions and small-molecule inhibition. Nucleic Acids Res. 2013 Jan;41(2):754-63. doi: 10.1093/nar/gks1085. Epub 2012 Nov 24. PubMed PMID: 23180800; PubMed Central PMCID: PMC3553987.