Carbromal

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591065

CAS#: 77-65-6

Description: Carbromal is a sedative and can also work as an anticancer drug.


Chemical Structure

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Carbromal
CAS# 77-65-6

Theoretical Analysis

MedKoo Cat#: 591065
Name: Carbromal
CAS#: 77-65-6
Chemical Formula: C7H13BrN2O2
Exact Mass: 236.016
Molecular Weight: 237.1
Elemental Analysis: C, 35.46; H, 5.53; Br, 33.70; N, 11.82; O, 13.50

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Nenesin; NSC 49191; NSC49191; NSC-49191

IUPAC/Chemical Name: Butanamide, N-(aminocarbonyl)-2-bromo-2-ethyl-

InChi Key: OPNPQXLQERQBBV-UHFFFAOYSA-N

InChi Code: InChI=1S/C7H13BrN2O2/c1-3-7(8,4-2)5(11)10-6(9)12/h3-4H2,1-2H3,(H3,9,10,11,12)

SMILES Code: CCC(CC)(Br)C(NC(N)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 237.1 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Oehmichen M, Ochs U, Meissner C. Regional potassium distribution in the brain in forensic relevant types of intoxication preliminary morphometric evaluation using a histochemical method. Neurotoxicology. 2001 Feb;22(1):99-107. PubMed PMID: 11307856.

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4: Maurer HH. Identification and differentiation of barbiturates, other sedative-hypnotics and their metabolites in urine integrated in a general screening procedure using computerized gas chromatography-mass spectrometry. J Chromatogr. 1990 Sep 14;530(2):307-26. PubMed PMID: 2079506.

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6: Kubicki S, Meyer C, Röhmel J. [The 4 second sleep spindle periodicity]. EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1986 Jun;17(2):55-61. German. PubMed PMID: 2874983.

7: Cockaerts P, Roets E, Hoogmartens J. Analysis of a complex analgesic formulation by high-performance liquid chromatography with column-switching. J Pharm Biomed Anal. 1986;4(3):367-76. PubMed PMID: 16867602.

8: Przybilla B, Ring J, Harle R, Galosi A. [Skin testing with the components of analgesics in patients with anaphylactoid hypersensitivity reactions to mild analgesics]. Hautarzt. 1985 Dec;36(12):682-7. German. PubMed PMID: 2935512.

9: Maes V, Huyghens L, Dekeyser J, Sevens C. Acute and chronic intoxication with carbromal preparations. J Toxicol Clin Toxicol. 1985;23(4-6):341-6. PubMed PMID: 2865375.

10: De Keyser J, Maes V, Malfait R, Segers O, Ebinger G. Bromism after prolonged use of carbromal. Acta Neurol Belg. 1984 Mar-Apr;84(2):69-74. PubMed PMID: 6145280.

11: De Broe ME, Verpooten GA, Christiaens MA, Rutsaert RJ, Holvoet J, Nagler J, Heyndrickx A. Clinical experience with prolonged combined hemoperfusion-hemodialysis treatment of severe poisoning. Artif Organs. 1981 Feb;5(1):59-66. PubMed PMID: 7247757.

12: Feuerman EJ, Brodsky F. Nonthrombocytopenic purpura induced by carbromal. Cutis. 1979 Apr;23(4):489-90. PubMed PMID: 34502.

13: Bode G, Garbe G, Stöckigt W, Förster B. [The influence of hypnotics on the development of morphological and biochemical wound reaction (author's transl)]. Z Rechtsmed. 1979 Mar 8;82(4):337-47. German. PubMed PMID: 34946.

14: Harstick K, Holloway CJ, Brunner G, Külpmann WR, Petry K. The removal of hypnotic drugs from human serum. A comparative investigation of the adsorptive properties of native and agarose-encapsulated resins and charcoal. Int J Artif Organs. 1979 Mar;2(2):87-95. PubMed PMID: 38209.

15: Külpmann WR. [A simple gas chromatographic method for the determination of hypnotics in the serum (author's transl)]. J Clin Chem Clin Biochem. 1979 Mar;17(3):115-21. German. PubMed PMID: 35581.

16: Graben N, Klöppel HA. [Metabolism of carbromal during detoxication with combined hemoperfusion and hemodialysis (author's transl)]. Med Klin. 1979 Feb 16;74(7):229-34. German. PubMed PMID: 33323.

17: National Toxicology Program. Bioassay of carbromal for possible carcinogenicity. Natl Cancer Inst Carcinog Tech Rep Ser. 1979;173:1-135. PubMed PMID: 12799690.

18: Eichelbaum M, Sonntag B, von Unruh G. Determination of monoureides in biological fluids by high-pressure-liquid-chromatography. Arch Toxicol. 1978 Dec 28;41(3):187-93. PubMed PMID: 32863.

19: Külpmann WR. [A simple gas-chromatographic method for the determination of 2,2-diethylallylacetamide in serum and its application in cases of poisoning (author's transl)]. Z Rechtsmed. 1978 Dec 20;82(3):205-9. German. PubMed PMID: 742211.

20: Külpmann WR, Oellerich M, Blume U, Schmidt E, Barthels M. [In vitro evaluation of adsorbents used in haemoperfusion (author's transl)]. Klin Wochenschr. 1978 Dec 1;56(23):1171-8. German. PubMed PMID: 30857.