WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562734
Description: MYRA-A is an inducer of apoptosis in a Myc-dependent manner. It acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.
MedKoo Cat#: 562734
Chemical Formula: C19H20N2O4
Exact Mass: 340.1423
Molecular Weight: 340.37
Elemental Analysis: C, 67.05; H, 5.92; N, 8.23; O, 18.80
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: MYRA-A; MYRA A; MYRAA; NSC-339585; NSC 339585; NSC339585;
IUPAC/Chemical Name: 2-[3-(Dimethylamino)propylamino]-1,4-dihydroxyanthracene-9,10-dione
InChi Key: PCIUVTQUMJMKAU-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H20N2O4/c1-21(2)9-5-8-20-13-10-14(22)15-16(19(13)25)18(24)12-7-4-3-6-11(12)17(15)23/h3-4,6-7,10,20,22,25H,5,8-9H2,1-2H3
SMILES Code: O=C1C2=C(C=CC=C2)C(C3=C(O)C=C(NCCCN(C)C)C(O)=C13)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 340.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Frenzel A, Zirath H, Vita M, Albihn A, Henriksson MA. Identification of cytotoxic drugs that selectively target tumor cells with MYC overexpression. PLoS One. 2011;6(11):e27988. doi: 10.1371/journal.pone.0027988. Epub 2011 Nov 23. PubMed PMID: 22132187; PubMed Central PMCID: PMC3223192.
2: Mo H, Henriksson M. Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6344-9. Epub 2006 Apr 10. PubMed PMID: 16606833; PubMed Central PMCID: PMC1435363.