ICR 283

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591039

CAS#: 38915-21-8

Description: ICR 283 is a therapeutic agent.


Chemical Structure

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ICR 283
CAS# 38915-21-8

Theoretical Analysis

MedKoo Cat#: 591039
Name: ICR 283
CAS#: 38915-21-8
Chemical Formula: C18H19Cl3N2O2
Exact Mass: 400.0512
Molecular Weight: 401.71
Elemental Analysis: C, 53.82; H, 4.77; Cl, 26.47; N, 6.97; O, 7.97

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: ICR 283; ICR-283; ICR283

IUPAC/Chemical Name: 9-Acridinamine, 6-chloro-N-(2-(2-chloroethoxy)ethyl)-2-methoxy-, hydrochloride

InChi Key: JBGKSGSGRPNJKB-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H18Cl2N2O2.ClH/c1-23-13-3-5-16-15(11-13)18(21-7-9-24-8-6-19)14-4-2-12(20)10-17(14)22-16;/h2-5,10-11H,6-9H2,1H3,(H,21,22);1H

SMILES Code: COC1=CC2=C(NCCOCCCl)C3=CC=C(Cl)C=C3N=C2C=C1.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 401.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Pandy V, Narasingam M, Vijeepallam K, Mohan S, Mani V, Mohamed Z. The ethyl acetate fraction of a methanolic extract of unripe noni (Morinda citrifolia Linn.) fruit exhibits a biphasic effect on the dopaminergic system in mice. Exp Anim. 2017 Aug 5;66(3):283-291. doi: 10.1538/expanim.16-0105. Epub 2017 Apr 26. PubMed PMID: 28450692; PubMed Central PMCID: PMC5543249.

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14: Song H, Luo J, Luo W, Weng J, Wang Z, Li B, Li D, Liu M. Inactivation of G-protein-coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through down-regulation of the ATF4 signaling pathway. J Biol Chem. 2008 Dec 26;283(52):36687-97. doi: 10.1074/jbc.M800721200. Epub 2008 Oct 27. PubMed PMID: 18955481; PubMed Central PMCID: PMC2605983.

15: Qin D, Gan Y, Shao K, Wang H, Li W, Wang T, He W, Xu J, Zhang Y, Kou Z, Zeng L, Sheng G, Esteban MA, Gao S, Pei D. Mouse meningiocytes express Sox2 and yield high efficiency of chimeras after nuclear reprogramming with exogenous factors. J Biol Chem. 2008 Nov 28;283(48):33730-5. doi: 10.1074/jbc.M806788200. Epub 2008 Sep 29. PubMed PMID: 18826945; PubMed Central PMCID: PMC2662282.

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