Noreximide
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MedKoo CAT#: 558011

CAS#: 3647-74-3

Description: Noreximide is a sedative.

Chemical Structure

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Noreximide
CAS# 3647-74-3
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 558011
Name: Noreximide
CAS#: 3647-74-3
Chemical Formula: C9H9NO2
Exact Mass: 163.06
Molecular Weight: 163.176
Elemental Analysis: C, 66.25; H, 5.56; N, 8.58; O, 19.61

Price and Availability

Size Price Availability Quantity
5g USD 195 2 Weeks
25g USD 330 2 Weeks
100g USD 565 2 Weeks
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Related CAS #: 3647-74-3 (exo-isomer)   6265-30-1 (endo-isomer)  

Synonym: Noreximide

IUPAC/Chemical Name: 4,7-Methano-1H-isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-

InChi Key: GPIUUMROPXDNRH-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H9NO2/c11-8-6-4-1-2-5(3-4)7(6)9(12)10-8/h1-2,4-7H,3H2,(H,10,11,12)

SMILES Code: O=C1NC(C2C(C3)C=CC3C12)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: Noreximide is a sedative.
In vitro activity: TBD
In vivo activity: TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 163.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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Reconstitution Calculator

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1: Tan HS, Pan PW. High-performance liquid chromatographic separation of noreximide and norendimide in bulk material, tablets and animal feed. J Chromatogr. 1987 Aug 28;404(1):233-41. PubMed PMID: 3680435.

2: Koch HP, Bykadi G, Ledesma B, Ritschel WA. Pharmacokinetics of noreximide in the beagle dog. Methods Find Exp Clin Pharmacol. 1982;4(8):587-90. PubMed PMID: 7169847.

3: Koch HP, Pischek G, Czejka M, Ritschel WA. Pharmacokinetic evaluation of norendimide in rats. Methods Find Exp Clin Pharmacol. 1982;4(8):581-5. PubMed PMID: 7169846.

4: Koch HP, Pischek G, Holzbecher M, Ritschel WA. Pharmacokinetic evaluation of noreximide in rats. Biopharm Drug Dispos. 1981 Jul-Sep;2(3):245-53. PubMed PMID: 7295881.