W-372 F-18

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341574

CAS#: 1206722-92-0

Description: W-372 F-18 is a biochemical.


Chemical Structure

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W-372 F-18
CAS# 1206722-92-0

Theoretical Analysis

MedKoo Cat#: 341574
Name: W-372 F-18
CAS#: 1206722-92-0
Chemical Formula: C14H918FN4OS
Exact Mass: 299.0506
Molecular Weight: 299.3139
Elemental Analysis: C, 56.18; H, 3.03; F, 6.01; N, 18.72; O, 5.35; S, 10.71

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: W-372 F-18.

IUPAC/Chemical Name: Imidazo(2',1':2,3)thiazolo(5,4-b)pyridine, 2-(6-(fluoro-18F)-3-pyridinyl)-7-methoxy-

InChi Key: CZEQPPMIFFXBLZ-HUYCHCPVSA-N

InChi Code: InChI=1S/C14H9FN4OS/c1-20-12-5-3-10-13(18-12)21-14-17-9(7-19(10)14)8-2-4-11(15)16-6-8/h2-7H,1H3/i15-1

SMILES Code: COC1=CC=C2C(SC3=NC(C4=CC=C([18F])N=C4)=CN32)=N1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 299.3139 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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6: Zhang C, Zhang Z, Lin KS, Lau J, Zeisler J, Colpo N, Perrin DM, Bénard F. Melanoma Imaging Using (18)F-Labeled α-Melanocyte-Stimulating Hormone Derivatives with Positron Emission Tomography. Mol Pharm. 2018 May 10. doi: 10.1021/acs.molpharmaceut.7b01113. [Epub ahead of print] PubMed PMID: 29714486.

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10: Loewenstein DA, Curiel RE, Rosselli M, Penate A, Greig-Custo MT, Bauer RM, Guinjoan SM, Hanson KS, Li C, Lizarraga G, Barker WW, Torres V, DeKosky S, Adjouadi M, Duara R. Semantic Intrusions and Failure to Recover From Semantic Interference in Mild Cognitive Impairment: Relationship to Amyloid and Cortical Thickness. Curr Alzheimer Res. 2018 Apr 27. doi: 10.2174/1567205015666180427122746. [Epub ahead of print] PubMed PMID: 29701153.

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13: Takemiya K, Ning X, Seo W, Wang X, Mohammad R, Joseph G, Titterington JS, Kraft CS, Nye JA, Murthy N, Goodman MM, Taylor WR. Novel PET and Near Infrared Imaging Probes for the Specific Detection of Bacterial Infections Associated With Cardiac Devices. JACC Cardiovasc Imaging. 2018 Apr 13. pii: S1936-878X(18)30207-9. doi: 10.1016/j.jcmg.2018.02.011. [Epub ahead of print] PubMed PMID: 29680350.

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15: Yoon SN. Follicular Lymphoma mimicking Metastatic Nodes on the F-18 FDG PET/CT and MRI for Staging of Endometrial Cancer. Nucl Med Mol Imaging. 2018 Apr;52(2):159-161. doi: 10.1007/s13139-016-0458-1. Epub 2016 Nov 5. PubMed PMID: 29662565; PubMed Central PMCID: PMC5897253.

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19: Toriihara A, Nakadate M, Fujioka T, Oyama J, Tsutsumi T, Asakage T, Tsunoda A, Tateishi U. Clinical Usefulness of 18F-FDG PET/CT for Staging Cancer of the External Auditory Canal. Otol Neurotol. 2018 Jun;39(5):e370-e375. doi: 10.1097/MAO.0000000000001791. PubMed PMID: 29649045.

20: Natarajan A, Chandra P, Purandare N, Agrawal A, Shah S, Puranik A, Rangarajan V. Role of Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Various Orbital Malignancies. Indian J Nucl Med. 2018 Apr-Jun;33(2):118-124. doi: 10.4103/ijnm.IJNM_135_17. PubMed PMID: 29643671; PubMed Central PMCID: PMC5883428.