W 77

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341566

CAS#: 118998-51-9

Description: W 77 is a biochemical.

Chemical Structure

W 77
CAS# 118998-51-9

Theoretical Analysis

MedKoo Cat#: 341566
Name: W 77
CAS#: 118998-51-9
Chemical Formula: C31H40N4O6S
Exact Mass: 596.27
Molecular Weight: 596.743
Elemental Analysis: C, 62.40; H, 6.76; N, 9.39; O, 16.09; S, 5.37

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: W 77; W-77; W77.

IUPAC/Chemical Name: p-(2-Aminoethyloxy)-N-(2-(4-benzyloxycarbonylpiperazinyl)-1-(p-methoxybenzyl)ethyl)-N-methylbenzenesulfonamide dihydrochloride


InChi Code: InChI=1S/C31H40N4O6S/c1-33(42(37,38)30-14-12-29(13-15-30)40-21-16-32)27(22-25-8-10-28(39-2)11-9-25)23-34-17-19-35(20-18-34)31(36)41-24-26-6-4-3-5-7-26/h3-15,27H,16-24,32H2,1-2H3

SMILES Code: CN(C(Cc1ccc(cc1)OC)CN2CCN(CC2)C(=O)OCc3ccccc3)S(=O)(=O)c4ccc(cc4)OCCN

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 596.743000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Macagnino S, Steinert T, Uhlmann C. [Evaluation of Suicide Risk Levels in Hospitals: Validity and Reliability Tests]. Psychiatr Prax. 2018 May;45(4):206-213. doi: 10.1055/s-0043-119244. Epub 2017 Dec 13. German. PubMed PMID: 29237197. 2: Wang H, Li H, Zeng FL, Xie CX. [Spatial Distribution and Global Potential Suitability Regions of Artemisia annua]. Zhong Yao Cai. 2015 Mar;38(3):460-6. Chinese. PubMed PMID: 26495642. 3: Ambye-Jensen M, Johansen KS, Didion T, Kádár Z, Meyer AS. Ensiling and hydrothermal pretreatment of grass: consequences for enzymatic biomass conversion and total monosaccharide yields. Biotechnol Biofuels. 2014 Jun 20;7:95. doi: 10.1186/1754-6834-7-95. eCollection 2014. PubMed PMID: 25024743; PubMed Central PMCID: PMC4096529. 4: Gibson J, Hussain J, Holsgrove S, Adams C, Green J. Quantifying peer interactions for research and clinical use: the Manchester Inventory for Playground Observation. Res Dev Disabil. 2011 Nov-Dec;32(6):2458-66. doi: 10.1016/j.ridd.2011.07.014. Epub 2011 Aug 9. PubMed PMID: 21831591. 5: Mostratos Z, Domeyer PR, Michalis D. Cancer mortality in Greece: where are we heading? A 20-year comparative study in four Greek counties. Cent Eur J Public Health. 2006 Sep;14(3):113-6. PubMed PMID: 17152221. 6: Chryssanthopoulos C, Williams C, Nowitz A. Influence of a carbohydrate-electrolyte solution ingested during running on muscle glycogen utilisation in fed humans. Int J Sports Med. 2002 May;23(4):279-84. PubMed PMID: 12015629. 7: Bar A, Razaphkovsky V, Wax E, Malka Y. Effect of age at molting on postmolting performance. Poult Sci. 2001 Jul;80(7):874-8. PubMed PMID: 11469648. 8: Marsh AP, Martin PE, Foley KO. Effect of cadence, cycling experience, and aerobic power on delta efficiency during cycling. Med Sci Sports Exerc. 2000 Sep;32(9):1630-4. PubMed PMID: 10994916. 9: Chamruspollert M, Sell JL. Transfer of dietary conjugated linoleic acid to egg yolks of chickens. Poult Sci. 1999 Aug;78(8):1138-50. PubMed PMID: 10472840. 10: Hurwitz S, Wax E, Nisenbaum Y, Ben-Moshe M, Plavnik I. The response of laying hens to induced molt as affected by strain and age. Poult Sci. 1998 Jan;77(1):22-31. PubMed PMID: 9469747. 11: Maeda O, Kikkawa F, Tamakoshi K, Obata NH, Mizuno K, Suganuma N, Tomoda Y, Kuzuya K, Ishikawa T, Hidaka H. A newly synthesized bifunctional inhibitor, CKA1083, enhances adriamycin activity against human ovarian carcinoma cells. Anticancer Res. 1997 May-Jun;17(3C):1985-92. PubMed PMID: 9216655. 12: Palmer GS, Noakes TD, Hawley JA. Effects of steady-state versus stochastic exercise on subsequent cycling performance. Med Sci Sports Exerc. 1997 May;29(5):684-7. PubMed PMID: 9140907. 13: Sandoval DM, Gernat AG. Evaluation of early feed restriction on egg size and hen performance. Poult Sci. 1996 Mar;75(3):311-4. PubMed PMID: 8778721. 14: Maeda O, Terasawa M, Ishikawa T, Oguchi H, Mizuno K, Kawai M, Kikkawa F, Tumoda Y, Hidaka H. A newly synthesized bifunctional inhibitor, W-77, enhances adriamycin activity against human ovarian carcinoma cells. Cancer Res. 1993 May 1;53(9):2051-6. PubMed PMID: 8097673. 15: Terasawa M, Nakano A, Kobayashi R, Hidaka H. Neurocalcin: a novel calcium-binding protein from bovine brain. J Biol Chem. 1992 Sep 25;267(27):19596-9. PubMed PMID: 1527077. 16: Tokumitsu H, Kobayashi R, Hidaka H. A calcium-binding protein from rabbit lung cytosol identified as the product of growth-regulated gene (2A9) and its binding proteins. Arch Biochem Biophys. 1991 Jul;288(1):202-7. Erratum in: Arch Biochem Biophys. 1991 Dec;291(2):401. PubMed PMID: 1898017. 17: Hattori Y, Katafuchi T, Koizumi K. Characterization of opioid-sensitive neurons in the anteroventral third ventricle region of polydipsic inbred mice in vitro. Brain Res. 1991 Jan 11;538(2):283-8. PubMed PMID: 1672830. 18: Fréminet A, Dallevet G, Guillet-Deniau I, Minaire Y. Comparison of glycogen store in two strains of rat and guinea-pig under fed and fasted conditions. Comp Biochem Physiol A Comp Physiol. 1984;79(1):53-9. PubMed PMID: 6148184. 19: Kresze GB, Ronft H. Pyruvate dehydrogenase complex from baker's yeast. 2. Molecular structure, dissociation, and implications for the origin of mitochondria. Eur J Biochem. 1981 Oct;119(3):581-7. PubMed PMID: 7030741.