WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562647
Description: ACA is an inhibitor of human immunodeficiency virus type 1 (HIV-1) replication. It acts by blocking Rev transport and activating TRPV1.
MedKoo Cat#: 562647
Chemical Formula: C13H14O4
Exact Mass: 234.08
Molecular Weight: 234.251
Elemental Analysis: C, 66.66; H, 6.02; O, 27.32
Synonym: ACA; 1-Acetoxychavicol acetate;
IUPAC/Chemical Name: [4-[(1S)-1-Acetyloxyprop-2-enyl]phenyl] acetate
InChi Key: JAMQIUWGGBSIKZ-ZDUSSCGKSA-N
InChi Code: InChI=1S/C13H14O4/c1-4-13(17-10(3)15)11-5-7-12(8-6-11)16-9(2)14/h4-8,13H,1H2,2-3H3/t13-/m0/s1
SMILES Code: CC(OC1=CC=C([C@@H](OC(C)=O)C=C)C=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 234.251 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Sung B, Prasad S, Yadav VR, Aggarwal BB. Cancer cell signaling pathways targeted by spice-derived nutraceuticals. Nutr Cancer. 2012;64(2):173-97. doi: 10.1080/01635581.2012.630551. Epub 2011 Dec 9. Review. PubMed PMID: 22149093; PubMed Central PMCID: PMC3645308.
2: Murakami A. Chemoprevention with phytochemicals targeting inducible nitric oxide synthase. Forum Nutr. 2009;61:193-203. doi: 10.1159/000212751. Epub 2009 Apr 7. Review. PubMed PMID: 19367123.
3: Murakami A, Ohigashi H. Targeting NOX, INOS and COX-2 in inflammatory cells: chemoprevention using food phytochemicals. Int J Cancer. 2007 Dec 1;121(11):2357-63. Review. PubMed PMID: 17893865.
4: Murakami A, Ohigashi H. Cancer-preventive anti-oxidants that attenuate free radical generation by inflammatory cells. Biol Chem. 2006 Apr;387(4):387-92. Review. PubMed PMID: 16606336.