W-15

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341523

CAS#: 93100-99-3

Description: W-15 is a biochemical.


Chemical Structure

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W-15
CAS# 93100-99-3

Theoretical Analysis

MedKoo Cat#: 341523
Name: W-15
CAS#: 93100-99-3
Chemical Formula: C19H21ClN2O2S
Exact Mass: 376.10
Molecular Weight: 376.899
Elemental Analysis: C, 60.55; H, 5.62; Cl, 9.41; N, 7.43; O, 8.49; S, 8.51

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: W 15; W-15; W15.

IUPAC/Chemical Name: 1-Phenylethylpiperidylidene-2-(4-chlorophenyl)sulfonamide

InChi Key: VJHXSSVOCOBVMI-XUTLUUPISA-N

InChi Code: InChI=1S/C19H21ClN2O2S/c20-17-9-11-18(12-10-17)25(23,24)21-19-8-4-5-14-22(19)15-13-16-6-2-1-3-7-16/h1-3,6-7,9-12H,4-5,8,13-15H2/b21-19+

SMILES Code: Clc1ccc(cc1)S(=O)(=O)\N=C\2/CCCCN2CCc3ccccc3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 376.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Reffet K, Lescanne E, Bobillier C, Aussedat C, Bakhos D. Hearing aids in patients with vestibular schwannoma: Interest of the auditory brainstem responses. Clin Otolaryngol. 2018 Mar 25. doi: 10.1111/coa.13099. [Epub ahead of print] PubMed PMID: 29575711.

2: Park Y, Kim BH, Lee SJ, Park HJ, Oh HK, Kim MS, Kook MS. Oxygen and Acrylic Acid Plasma Treatment on Titanium Mesh for Improving the Hydroxyapatite Formation. J Nanosci Nanotechnol. 2018 Feb 1;18(2):1303-1307. doi: 10.1166/jnn.2018.14860. PubMed PMID: 29448578.

3: Huang XP, Che T, Mangano TJ, Le Rouzic V, Pan YX, Majumdar S, Cameron MD, Baumann MH, Pasternak GW, Roth BL. Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo. JCI Insight. 2017 Nov 16;2(22). pii: 97222. doi: 10.1172/jci.insight.97222. [Epub ahead of print] PubMed PMID: 29202454; PubMed Central PMCID: PMC5752382.

4: Abedin F, Roughton B, Ye Q, Spencer P, Camarda K. Computer-aided Molecular Design of Water Compatible Visible Light Photosensitizers for Dental Adhesive. Chem Eng Sci. 2017 Feb 23;159:131-139. doi: 10.1016/j.ces.2016.09.033. Epub 2016 Sep 30. PubMed PMID: 29176909; PubMed Central PMCID: PMC5699481.

5: Arslan D, Kuştarcı A. The effect of the KTP laser on smear layer and temperature change: an in vitro study. Lasers Med Sci. 2018 Jan;33(1):149-157. doi: 10.1007/s10103-017-2374-8. Epub 2017 Nov 6. PubMed PMID: 29105009.

6: Ige EO, Raj MK, Dare AA, Chakraborty S. Micromechanical properties of biomedical hydrogel for application as microchannel elastomer. J Mech Behav Biomed Mater. 2018 Jan;77:217-224. doi: 10.1016/j.jmbbm.2017.09.011. Epub 2017 Sep 14. PubMed PMID: 28946052.

7: Montealegre-Meléndez I, Arévalo C, Perez-Soriano EM, Neubauer E, Rubio-Escudero C, Kitzmantel M. Analysis of the Influence of Starting Materials and Processing Conditions on the Properties of W/Cu Alloys. Materials (Basel). 2017 Feb 8;10(2). pii: E142. doi: 10.3390/ma10020142. PubMed PMID: 28772502; PubMed Central PMCID: PMC5459155.

8: Arslan D, Kustarci A. Efficacy of photon-initiated photoacoustic streaming on apically extruded debris with different preparation systems in curved canals. Int Endod J. 2018 Jan;51 Suppl 1:e65-e72. doi: 10.1111/iej.12816. Epub 2017 Aug 1. PubMed PMID: 28708251.

9: Kirtane AR, Rothenberger MK, Frieberg A, Nephew K, Schultz-Darken N, Schmidt T, Reimann T, Haase AT, Panyam J. Evaluation of Vaginal Drug Levels and Safety of a Locally Administered Glycerol Monolaurate Cream in Rhesus Macaques. J Pharm Sci. 2017 Jul;106(7):1821-1827. doi: 10.1016/j.xphs.2017.03.030. Epub 2017 Apr 4. PubMed PMID: 28389267; PubMed Central PMCID: PMC5511513.

10: Peach J, Czajka A, Hazell G, Hill C, Mohamed A, Pegg JC, Rogers SE, Eastoe J. Tuning Micellar Structures in Supercritical CO(2) Using Surfactant and Amphiphile Mixtures. Langmuir. 2017 Mar 14;33(10):2655-2663. doi: 10.1021/acs.langmuir.7b00324. Epub 2017 Mar 2. PubMed PMID: 28215094.

11: Dhananjayan I, Kathiroli S, Subramani S, Veerasamy V. Ameliorating effect of betanin, a natural chromoalkaloid by modulating hepatic carbohydrate metabolic enzyme activities and glycogen content in streptozotocin - nicotinamide induced experimental rats. Biomed Pharmacother. 2017 Apr;88:1069-1079. doi: 10.1016/j.biopha.2017.01.146. Epub 2017 Feb 7. PubMed PMID: 28192880.

12: Gonçalves DA, Soncin AC, Donati GL, Dos Santos MC. Determination of Trace Elements in Cow Placenta by Tungsten Coil Atomic Emission Spectrometry. Biol Trace Elem Res. 2017 Aug;178(2):228-234. doi: 10.1007/s12011-016-0926-6. Epub 2017 Jan 16. PubMed PMID: 28092076.

13: Matczuk AK, Niczyporuk JS, Kuczkowski M, Woźniakowski G, Nowak M, Wieliczko A. Whole genome sequencing of Fowl aviadenovirus A - a causative agent of gizzard erosion and ulceration, in adult laying hens. Infect Genet Evol. 2017 Mar;48:47-53. doi: 10.1016/j.meegid.2016.12.008. Epub 2016 Dec 8. PubMed PMID: 27940213.

14: Brill MS, Kleele T, Ruschkies L, Wang M, Marahori NA, Reuter MS, Hausrat TJ, Weigand E, Fisher M, Ahles A, Engelhardt S, Bishop DL, Kneussel M, Misgeld T. Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination. Neuron. 2016 Nov 23;92(4):845-856. doi: 10.1016/j.neuron.2016.09.049. Epub 2016 Oct 20. PubMed PMID: 27773584; PubMed Central PMCID: PMC5133389.

15: Zhou J, Wu Y, Wang C, Cheng Q, Han S, Wang X, Zhang J, Deng L, Zhao D, Du L, Cao H, Liang Z, Huang Y, Dong A. pH-Sensitive Nanomicelles for High-Efficiency siRNA Delivery in Vitro and in Vivo: An Insight into the Design of Polycations with Robust Cytosolic Release. Nano Lett. 2016 Nov 9;16(11):6916-6923. Epub 2016 Oct 17. PubMed PMID: 27748606.

16: Keszte J, Danker H, Dietz A, Meister E, Pabst F, Guntinas-Lichius O, Oeken J, Singer S, Meyer A. Course of psychiatric comorbidity and utilization of mental health care after laryngeal cancer: a prospective cohort study. Eur Arch Otorhinolaryngol. 2017 Mar;274(3):1591-1599. doi: 10.1007/s00405-016-4340-7. Epub 2016 Oct 15. PubMed PMID: 27744529.

17: McAllister CT, Scott Seville R, Hartdegen R. Two new species of coccidia (Apicomplexa: Eimeriidae) from leaf-tailed geckos, Uroplatus spp. (Sauria: Gekkonidae) from Madagascar, including a new host of Eimeria brygooi Upton & Barnard, 1987. Syst Parasitol. 2016 Oct;93(8):815-23. doi: 10.1007/s11230-016-9660-x. Epub 2016 Sep 14. PubMed PMID: 27638735; PubMed Central PMCID: PMC5145816.

18: Sobouti F, Dadgar S, Sanikhaatam Z, Nateghian N, Saravi MG. Effects of two erbium-doped yttrium aluminum garnet lasers and conventional treatments as composite surface abrasives on the shear bond strength of metal brackets bonded to composite resins. J Orthod Sci. 2016 Jan-Mar;5(1):18-24. doi: 10.4103/2278-0203.176654. PubMed PMID: 26998473; PubMed Central PMCID: PMC4778173.

19: Zhang F, Meng X, Feng C, Ran W, Yu G, Zhang Y, Shen Q. Hydrolytic Amino Acids Employed as a Novel Organic Nitrogen Source for the Preparation of PGPF-Containing Bio-Organic Fertilizer for Plant Growth Promotion and Characterization of Substance Transformation during BOF Production. PLoS One. 2016 Mar 14;11(3):e0149447. doi: 10.1371/journal.pone.0149447. eCollection 2016. PubMed PMID: 26974549; PubMed Central PMCID: PMC4790899.

20: Lacôte E. Polymer-containing Organo-Polyoxometalate: Towards New Catalytic Object. Chimia (Aarau). 2016;70(1-2):29-33. doi: 10.2533/chimia.2016.29. PubMed PMID: 26931214.