WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 341503
Description: Xylure is a biochemical.
MedKoo Cat#: 341503
Chemical Formula: C12H20N2O5Si
Exact Mass: 300.1141
Molecular Weight: 300.386
Elemental Analysis: C, 47.98; H, 6.71; N, 9.33; O, 26.63; Si, 9.35
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
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IUPAC/Chemical Name: Uridine, 2'-deoxy-5-(trimethylsilyl)-
InChi Key: DZEOQTVJWBLBOT-QXFUBDJGSA-N
InChi Code: InChI=1S/C12H20N2O5Si/c1-20(2,3)9-5-14(12(18)13-11(9)17)10-4-7(16)8(6-15)19-10/h5,7-8,10,15-16H,4,6H2,1-3H3,(H,13,17,18)/t7-,8+,10+/m0/s1
SMILES Code: OC[C@@H]1[C@H](C[C@H](N2C(NC(C([Si](C)(C)C)=C2)=O)=O)O1)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 300.386 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Ektova LV, Iartseva IV, Khorosheva EV, Ivanova TP, Iavorskaia NP, Mel'nik SIa. [Synthesis and biological properties of pyrimidine 2'-deoxynucleosides modified by a residue of quinaldic acid]. Bioorg Khim. 1995 Aug;21(8):625-31. Russian. PubMed PMID: 8540903.
2: Bektemirov TA, Chekunova ZV, Andzhaparidze OG. [Antiviral activity of the 1-alpha- and beta-desoxy-D-ribofuranosides of 5-trimethylsilyl uracil]. Vopr Virusol. 1987 Jan-Feb;32(1):114-6. Russian. PubMed PMID: 3033901.
3: Chekunova EV, Marennikova SS, Mel'nik SIa, Preobrazhenskaia MN, Zaguliaeva OA. [Antiherpetic activity of xylure]. Vopr Virusol. 1985 Jul-Aug;30(4):444-6. Russian. PubMed PMID: 3904209.
4: Zhirnov OP, Ovcharenko AV, Bukrinskaia AG. [Blocking of Sindbis virus replication in the body of infected mice using an inhibitor of chymotrypsin-like proteases]. Vopr Virusol. 1985 Jul-Aug;30(4):450-3. Russian. PubMed PMID: 2998094.