Dacuronium bromide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581187

CAS#: 27115-86-2

Description: Dacuronium bromide is an aminosteroid neuromuscular blocking agent Pancuronium (P178500) with much weaker activity which was never marketed. It acts as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR).

Chemical Structure

Dacuronium bromide
CAS# 27115-86-2

Theoretical Analysis

MedKoo Cat#: 581187
Name: Dacuronium bromide
CAS#: 27115-86-2
Chemical Formula: C33H58Br2N2O3
Exact Mass: 688.2814
Molecular Weight: 690.65
Elemental Analysis: C, 57.39; H, 8.47; Br, 23.14; N, 4.06; O, 6.95

Price and Availability

Size Price Availability Quantity
10.0mg USD 330.0 2 Weeks
100.0mg USD 1690.0 2 Weeks
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Synonym: Dacuronium bromide; Dacuronii bromidum; EINECS 248-233-9; NB 68; NB68; ORG 6368;

IUPAC/Chemical Name: 2-beta, 16-beta-Dipiperidino-5-alpha-androstan-3-alpha,17-beta-diol 3-acetate dimethobromide



SMILES Code: C[C@@]12[C@@H](O)[C@@H](N3CCCCC3)C[C@@]1([H])[C@]4([H])CC[C@@]5([H])C[C@H](OC(C)=O)[C@@H](N6CCCCC6)C[C@]5(C)[C@@]4([H])CC2.CBr.CBr

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Biological target: Dacuronium bromide acts as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR).

Preparing Stock Solutions

The following data is based on the product molecular weight 690.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Norman J, Katz RL. Some effects of the steroidal muscle relaxant, dacuronium bromide, in anaesthetized patients. Br J Anaesth. 1971 Apr;43(4):313-9. PubMed PMID: 4252525.

2. Marshall, I.G. et al.: Br. J. Anaesth., 55, 703 (1983); Norman, J. et al.: Br. J. Anaesth., 43, 313 (1971); Durant, N.N. et al.: J. Pharm. Pharmacol., 31, 831 (1979);