WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 581187
Description: Dacuronium bromide is an aminosteroid neuromuscular blocking agent Pancuronium (P178500) with much weaker activity which was never marketed. It acts as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR).
MedKoo Cat#: 581187
Name: Dacuronium bromide
Chemical Formula: C33H58Br2N2O3
Exact Mass: 688.2814
Molecular Weight: 690.65
Elemental Analysis: C, 57.39; H, 8.47; Br, 23.14; N, 4.06; O, 6.95
Synonym: Dacuronium bromide; Dacuronii bromidum; EINECS 248-233-9; NB 68; NB68; ORG 6368;
IUPAC/Chemical Name: 2-beta, 16-beta-Dipiperidino-5-alpha-androstan-3-alpha,17-beta-diol 3-acetate dimethobromide
InChi Key: DCMGIRFMSWIIHH-LKRYSLHCSA-N
InChi Code: DCMGIRFMSWIIHH-LKRYSLHCSA-N
SMILES Code: C[C@@]12[C@@H](O)[C@@H](N3CCCCC3)C[C@@]1([H])[C@]4([H])CC[C@@]5([H])C[C@H](OC(C)=O)[C@@H](N6CCCCC6)C[C@]5(C)[C@@]4([H])CC2.CBr.CBr
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
|Biological target:||Dacuronium bromide acts as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR).|
The following data is based on the product molecular weight 690.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Norman J, Katz RL. Some effects of the steroidal muscle relaxant, dacuronium bromide, in anaesthetized patients. Br J Anaesth. 1971 Apr;43(4):313-9. PubMed PMID: 4252525.
2. Marshall, I.G. et al.: Br. J. Anaesth., 55, 703 (1983); Norman, J. et al.: Br. J. Anaesth., 43, 313 (1971); Durant, N.N. et al.: J. Pharm. Pharmacol., 31, 831 (1979);