UNC-926 free base
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 555216

CAS#: 1184136-10-4 (free base)

Description: UNC-926 is a L3MBTL1 domain inhibitor. UNC-926 binds to the MBT domain of the L3MBTL1 protein (Kd = 3.9 μM).

Chemical Structure

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UNC-926 free base
CAS# 1184136-10-4 (free base)
Instruction

Theoretical Analysis

MedKoo Cat#: 555216
Name: UNC-926 free base
CAS#: 1184136-10-4 (free base)
Chemical Formula: C16H21BrN2O
Exact Mass: 336.08
Molecular Weight: 337.261
Elemental Analysis: C, 56.98; H, 6.28; Br, 23.69; N, 8.31; O, 4.74

Price and Availability

Size Price Availability Quantity
100mg USD 750
200mg USD 1250
500mg USD 1850
1g USD 2850
2g USD 4250
5g USD 6950
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Related CAS #: 1782573-49-2 (HCl)   1184136-10-4 (free base)   1581296-53-8 (TFA)    

Synonym: UNC-926 free base; UNC-926; UNC926; UNC 926.

IUPAC/Chemical Name: (3-Bromophenyl)[4-(1-pyrrolidinyl)-1-piperidinyl]methanone

InChi Key: OWGLFIKZKQOYHZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H21BrN2O/c17-14-5-3-4-13(12-14)16(20)19-10-6-15(7-11-19)18-8-1-2-9-18/h3-5,12,15H,1-2,6-11H2

SMILES Code: O=C(C1=CC=CC(Br)=C1)N2CCC(N3CCCC3)CC2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 337.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Zhou H, Che X, Bao G, Wang N, Peng L, Barnash KD, Frye SV, James LI, Bai X.
Design, synthesis, and protein methyltransferase activity of a unique set of
constrained amine containing compounds. Bioorg Med Chem Lett. 2016 Sep
15;26(18):4436-4440. doi: 10.1016/j.bmcl.2016.08.004. Epub 2016 Aug 3. PubMed
PMID: 27528434; PubMed Central PMCID: PMC4996710.