HBX19818
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 562449

CAS#: 1426944-49-1

Description: HBX19818 is a selective inhibitor of USP7.

Chemical Structure

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HBX19818
CAS# 1426944-49-1
Product data Instruction

Theoretical Analysis

MedKoo Cat#: 562449
Name: HBX19818
CAS#: 1426944-49-1
Chemical Formula: C25H28ClN3O
Exact Mass: 421.19
Molecular Weight: 421.969
Elemental Analysis: C, 71.16; H, 6.69; Cl, 8.40; N, 9.96; O, 3.79

Price and Availability

Size Price Availability Quantity
25mg USD 250 2 Weeks
50mg USD 450 2 Weeks
100mg USD 750 2 Weeks
200mg USD 1250 2 Weeks
500mg USD 2850 2 Weeks
1g USD 3850 2 Weeks
2g USD 6450 2 Weeks
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Synonym: HBX19818; HBX-19818; HBX 19818;

IUPAC/Chemical Name: 9-Chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-2-acridinecarboxamide

InChi Key: ZCALMLVWZSQGGR-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H28ClN3O/c1-29(17-18-8-3-2-4-9-18)15-7-14-27-25(30)19-12-13-23-21(16-19)24(26)20-10-5-6-11-22(20)28-23/h2-4,8-9,12-13,16H,5-7,10-11,14-15,17H2,1H3,(H,27,30)

SMILES Code: O=C(C1=CC2=C(Cl)C3=C(CCCC3)N=C2C=C1)NCCCN(C)CC4=CC=CC=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Product Data:
Product Data
Instruction:
View handling instruction
Biological target: HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM.
In vitro activity: TBD
In vivo activity: TBD

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 12.5 29.62
Ethanol 5.0 0.47
Water 5.0 0.47

Preparing Stock Solutions

The following data is based on the product molecular weight 421.97 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol: TBD
In vitro protocol: TBD
In vivo protocol: TBD

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