WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 341242
Description: Yomogin is a biochemical.
MedKoo Cat#: 341242
Chemical Formula: C15H16O3
Exact Mass: 244.1099
Molecular Weight: 244.29
Elemental Analysis: C, 73.75; H, 6.60; O, 19.65
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
IUPAC/Chemical Name: 2-Naphthaleneacetic acid, 1,2beta,3,4,4a,7-hexahydro-3alpha-hydroxy-4aalpha,8-dimethyl-alpha-methylene-7-oxo-, gamma-lactone
InChi Key: ONPJVBQNWRHOKG-WDBKCZKBSA-N
InChi Code: InChI=1S/C15H16O3/c1-8-10-6-11-9(2)12(16)4-5-15(11,3)7-13(10)18-14(8)17/h4-5,10,13H,1,6-7H2,2-3H3/t10-,13-,15-/m1/s1
SMILES Code: O=C(O[C@H]1[C@@H]2CC3=C(C)C(C=C[C@]3(C)C1)=O)C2=C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 244.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Natividad GM, Broadley KJ, Kariuki B, Kidd EJ, Ford WR, Simons C. Actions of Artemisia vulgaris extracts and isolated sesquiterpene lactones against receptors mediating contraction of guinea pig ileum and trachea. J Ethnopharmacol. 2011 Sep 1;137(1):808-16. doi: 10.1016/j.jep.2011.06.042. Epub 2011 Jul 5. PubMed PMID: 21762766.
2: Jeong SH, Koo SJ, Ha JH, Ryu SY, Park HJ, Lee KT. Induction of apoptosis by yomogin in human promyelocytic leukemic HL-60 cells. Biol Pharm Bull. 2004 Jul;27(7):1106-11. PubMed PMID: 15256749.
3: Kim SH, Kim TS. Synergistic induction of 1,25-dihydroxyvitamin D(3)- and all-trans-retinoic acid-induced differentiation of HL-60 leukemia cells by yomogin, a sesquiterpene lactone from Artemisia princeps. Planta Med. 2002 Oct;68(10):886-90. PubMed PMID: 12391550.
4: Tigno XT, de Guzman F, Flora AM. Phytochemical analysis and hemodynamic actions of Artemisia vulgaris L. Clin Hemorheol Microcirc. 2000;23(2-4):167-75. PubMed PMID: 11321437.
5: Tigno XT, Gumila E. In vivo microvascular actions of Artemisia vulgaris L. in a model of ischemia-reperfusion injury in the rat intestinal mesentery. Clin Hemorheol Microcirc. 2000;23(2-4):159-65. PubMed PMID: 11321436.
6: Ryu SY, Oak MH, Kim KM. Yomogin inhibits the degranulation of mast cells and the production of the nitric oxide in activated RAW 264.7 cells. Planta Med. 2000 Mar;66(2):171-3. PubMed PMID: 10763594.
7: Ryu JH, Lee HJ, Jeong YS, Ryu SY, Han YN. Yomogin, an inhibitor of nitric oxide production in LPS-activated macrophages. Arch Pharm Res. 1998 Aug;21(4):481-4. PubMed PMID: 9875481.