Yohimbic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341213

CAS#: 522-87-2

Description: Yohimbic acid is a biochemical.


Chemical Structure

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Yohimbic acid
CAS# 522-87-2

Theoretical Analysis

MedKoo Cat#: 341213
Name: Yohimbic acid
CAS#: 522-87-2
Chemical Formula: C20H24N2O3
Exact Mass: 340.1787
Molecular Weight: 340.423
Elemental Analysis: C, 70.57; H, 7.11; N, 8.23; O, 14.10

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Yohimbic acid; NSC-95096; NSC 95096; NSC95096.

IUPAC/Chemical Name: 17alpha-Hydroxyyohimban-16alpha-carboxylic acid

InChi Key: AADVZSXPNRLYLV-GKMXPDSGSA-N

InChi Code: InChI=1S/C20H24N2O3/c23-17-6-5-11-10-22-8-7-13-12-3-1-2-4-15(12)21-19(13)16(22)9-14(11)18(17)20(24)25/h1-4,11,14,16-18,21,23H,5-10H2,(H,24,25)/t11-,14-,16-,17-,18+/m0/s1

SMILES Code: [H][C@]12C(NC3=C4C=CC=C3)=C4CCN1C[C@@]5(CC[C@H](O)[C@H](C(O)=O)[C@]5(C2)[H])[H]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 340.423 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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1: Lucas D, Neal-Kababick J, Zweigenbaum J. Characterization and quantitation of yohimbine and its analogs in botanicals and dietary supplements using LC/QTOF-MS and LC/QQQ-MS for determination of the presence of bark extract and yohimbine adulteration. J AOAC Int. 2015 Mar-Apr;98(2):330-5. doi: 10.5740/jaoacint.14-246. PubMed PMID: 25905738.

2: RAYMOND-HAMET. [ON THE SUCCESSIVE STAGES OF THE SYMPATHICOLYTIC ACTIVITY OF YOHIMBIC ACID]. C R Hebd Seances Acad Sci. 1963 Oct 14;257:2351-4. French. PubMed PMID: 14093965.

3: ARRIGO A, COSI V, SAVOLDI F. [EEG study of the central action of yohimbine and yohimbic acid. (Experimental research)]. Boll Soc Ital Biol Sper. 1961 Aug 31;37:787-90. Italian. PubMed PMID: 13862577.

4: RAYMOND HAMET. [Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline]. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5. French. PubMed PMID: 13854468.

5: KLUPP H. [Pharmacological studies on yohimbic acid ethyl ester (A 38) and 4-=2-(p-butoxyphenyl)-1,3-dioxolan-2-ylmethyl=-morpholine methobromide (Q 160) as well as the influence of these substances on reserpine action]. Arzneimittelforschung. 1955 Aug;5(8):432-6. German. PubMed PMID: 13276244.

6: RAYMOND-HAMET. [Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid]. C R Hebd Seances Acad Sci. 1951 Oct 29;233(18):1069-71. Undetermined Language. PubMed PMID: 14896545.