Tamitinol

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 584384

CAS#: 61711-37-3

Description: Tamitinol, also known as EMD 21 657, is a neurotropic drug that has been found to help symptoms of obsessive rumination in conjunction with maprotiline.

Chemical Structure

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Tamitinol
CAS# 61711-37-3
Instruction

Theoretical Analysis

MedKoo Cat#: 584384
Name: Tamitinol
CAS#: 61711-37-3
Chemical Formula: C12H20N2OS
Exact Mass: 240.13
Molecular Weight: 240.365
Elemental Analysis: C, 59.96; H, 8.39; N, 11.65; O, 6.66; S, 13.34

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Synonym: Tamitinol; Emd 21657; Emd21657; Emd-21657; EMD 21 657

IUPAC/Chemical Name: 3-Pyridinol, 4-(2-(ethylamino)ethyl)-2-methyl-5-((methylthio)methyl)-

InChi Key: AIYWGDYVMBTAHH-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H20N2OS/c1-4-13-6-5-11-10(8-16-3)7-14-9(2)12(11)15/h7,13,15H,4-6,8H2,1-3H3

SMILES Code: OC1=C(CCNCC)C(CSC)=CN=C1C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 240.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Noël G, Jeanmart M, Reinhardt B. Treatment of the organic brain syndrome in the elderly. A double-blind comparison on the effects of a neurotropic drug and placebo. Neuropsychobiology. 1983;10(2-3):90-3. PubMed PMID: 6371575.

2: Lehmann E, Kretschmar JH, Brauer H, Reinhardt B. Interaction of changes in hospital environment and neurotropic co-medication in chronic psychiatric inpatient. A placebo controlled double-blind study. Pharmacopsychiatria. 1982 Mar;15(2):57-60. PubMed PMID: 7043497.

3: Sanz R, Bettschart W, Reinhardt B. Tamitinol in paedopsychiatric out-patient therapy. Pharmatherapeutica. 1981;3(1):40-5. PubMed PMID: 7323108.

4: Pöldinger W, Reinhardt B. Neurotropic drugs as co-medication to psychotropics. Combined administration of a neurotropic drug and a tetracyclic antidepressant. Int Pharmacopsychiatry. 1980;15(3):137-42. PubMed PMID: 7016800.