WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 581158

CAS#: 56548-51-7

Description: Dabequin is an aminoquinoline derivative. which is claimed to have pharmacological activity against Plasmodium fukiparum.

Chemical Structure

CAS# 56548-51-7

Theoretical Analysis

MedKoo Cat#: 581158
Name: Dabequin
CAS#: 56548-51-7
Chemical Formula: C19H29N3O8P2
Exact Mass:
Molecular Weight: 489.4
Elemental Analysis: C, 46.63; H, 5.97; N, 8.59; O, 26.15; P, 12.66

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Dabequin; G 800; dabechin

IUPAC/Chemical Name: 1,2-Ethanediamine, N'-benzo(g)quinolin-4-yl-N,N-diethyl-, phosphate (1:2)


InChi Code: InChI=1S/C19H23N3.2H3O4P/c1-3-22(4-2)12-11-21-18-9-10-20-19-14-16-8-6-5-7-15(16)13-17(18)19;2*1-5(2,3)4/h5-10,13-14H,3-4,11-12H2,1-2H3,(H,20,21);2*(H3,1,2,3,4)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 489.4 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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1: Pomortseva IV, Ovchinnikova LK, Shcheglova NV. [The influence of the Soviet antimalarial preparation dabequin on the hemostatic system and on the anticoagulant effect of heparin]. Farmakol Toksikol. 1990 Jan-Feb;53(1):59-62. Russian. PubMed PMID: 2328805.

2: Tápanes RD, Ramos F, Febles M, Pérez Avila J. Determination of dabequin in biological fluids by gas chromatography with a nitrogen-selective detector. J Chromatogr. 1989 Aug 25;493(1):202-9. PubMed PMID: 2778013.

3: Frol'tsova AE, Kharchenko NM, Lebedeva MN, Pylev LN. [Possible carcinogenic activity of the Soviet antimalarial dabequin in a chronic experiment in animals]. Med Parazitol (Mosk). 1984 Nov-Dec;(6):6-13. Russian. PubMed PMID: 6530977.

4: Lur'e AA, Dinh TT, Le DD. [Pharmacokinetics of the new antimalarial preparation dabequin studied in monkeys]. Med Parazitol (Mosk). 1983 Jul-Aug;(4):23-9. Russian. PubMed PMID: 6633430.

5: Kouznetsov RL, Rooney W, Wernsdorfer WH, El Gaddal AA, Payne D, Abdalla RE. Use of the in vitro microtechnique for the assessment of drug sensitivity of Plasmodium falciparum in Sennar, Sudan. Bull World Health Organ. 1980;58(5):785-9. PubMed PMID: 7028301; PubMed Central PMCID: PMC2395992.

6: Ivanina TA, Lebedeva MN. [Comparative study of the effect of the antimalarials dabequin and chloroquine on retinal ultrastructure in the rat]. Vestn Oftalmol. 1982 May-Jun;(3):53-6. Russian. PubMed PMID: 7112855.

7: Moshkovskiĭ ShD, Rabinovich SA, Masakovskaia EV, Voronina ZK, Dadasheva NR. [General characteristics of the chemotherapeutic properties of a new experimental antimalarial preparation dabequin]. Med Parazitol (Mosk). 1981 Jul-Aug;50(4):27-33. Russian. PubMed PMID: 7024771.

8: Zhang JX, Lin BY, Pan YR, Zheng H, Fang Y. [Studies on the establishment of malarial animal model of short-term relapse. II. The phenomenon of sustained special ring form parasitemia in Plasmodium cynomolgi infection]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1992;10(4):250-4. Chinese. PubMed PMID: 1303329.

9: Muñoz E, Tapanes R, Perez G, Febles M, Ramos F. [The fluorimetric determination of dabequin in biological fluids]. Med Parazitol (Mosk). 1989 May-Jun;(3):53-5. Russian. PubMed PMID: 2779492.

10: Dzhabarova VI. [Larvicidal activity of acrichine and dabechine injected into a hydatid cyst by electrophoresis: experimental study]. Med Parazitol (Mosk). 2002 Apr-Jun;(2):43-5. Russian. PubMed PMID: 12214525.

11: Huang LS. [Progress in the pharmaceutical chemistry of antimalarial agents during the last 2 decades]. Yao Xue Xue Bao. 1983 Jul;18(7):553-60. Chinese. PubMed PMID: 6606935.

12: SUBIC CERNEKA Z. [A CASE OF PREMATURE INFANT WEIGHING 800 G]. Srp Arh Celok Lek. 1964 Nov;92:1115-7. Undetermined Language. PubMed PMID: 14333459.

13: Ivanina TA, Lebedeva MN. [Electron microscopic and electrophysiological study of the effect of the antimalarials dabequine and chloroquine on the retina of white rats]. Med Parazitol (Mosk). 1982 Jul-Aug;51(4):21-6. Russian. PubMed PMID: 7132919.

14: Lebedeva MN, Brusilovskaia VM. [Acute toxic action of combinations of a new antimalarial preparation, dabequine]. Med Parazitol (Mosk). 1980 Nov-Dec;49(6):27-31. Russian. PubMed PMID: 7207380.

15: Fedorova OV, Khomchenovskiĭ EI. [The antimalarial action of Soviet artemisinine in Plasmodium berghei schizont infection in mice]. Med Parazitol (Mosk). 1988 Sep-Oct;(5):11-5. Russian. PubMed PMID: 3075259.

16: Frol'tsova AE, Astaf'eva IP, Lebedeva MN, Lychko ND. [The Soviet antimalarial preparation dabequine studied for the presence of mutagenic activity]. Med Parazitol (Mosk). 1984 Jul-Aug;(4):16-21. Russian. PubMed PMID: 6384756.

17: Kuznetsov RL, Kilama V, Peĭn D, Kampbell SS, Stori D. [Effectiveness of treatment with chloroquine, fansidar and dabequin of Plasmodium falciparum carriers, residing in a hyperendemic focus of malaria (the city of Bagamoyo, Northeastern Tanzania)]. Med Parazitol (Mosk). 1985 Jul-Aug;(4):15-9. Russian. PubMed PMID: 3903459.

18: Kharitonova SI. [Quantitative analysis of dabequin by titration in a nonaqueous medium]. Farmatsiia. 1979 Nov-Dec;28(6):56-7. Russian. PubMed PMID: 520605.