WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 341171
Description: YM 26567-1 is a biochemical.
MedKoo Cat#: 341171
Name: YM 26567-1
Chemical Formula: C33H40O7
Exact Mass: 548.2774
Molecular Weight: 548.676
Elemental Analysis: C, 72.24; H, 7.35; O, 20.41
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: YM 26567-1; YM-26567-1; YM26567-1.
IUPAC/Chemical Name: 1-Dodecanone, 1-(3-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxyphenyl)-
InChi Key: JGXZVDAPLSTBGZ-VAVYLYDRSA-N
InChi Code: InChI=1S/C33H40O7/c1-2-3-4-5-6-7-8-9-10-11-26(36)32-28(38)20-27(37)31(33(32)39)25-19-29(21-12-14-22(34)15-13-21)40-30-18-23(35)16-17-24(25)30/h12-18,20,25,29,34-35,37-39H,2-11,19H2,1H3/t25-,29-/m1/s1
SMILES Code: C(CCCCCCCCCCC)(=O)c1c(c(c(cc1O)O)[C@@H]1C[C@@H](Oc2c1ccc(c2)O)c1ccc(cc1)O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 548.676 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Miyake A, Yamamoto H, Kubota E, Hamaguchi K, Kouda A, Honda K, Kawashima H. Suppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2. Br J Pharmacol. 1993 Sep;110(1):447-53. PubMed PMID: 8220906; PubMed Central PMCID: PMC2176023.
2: Miyake A, Yamamoto H, Takebayashi Y, Imai H, Honda K. The novel natural product YM-26567-1 [(+)-trans-4-(3-dodecanoyl-2,4,6- trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman]: a competitive inhibitor of group II phospholipase A2. J Pharmacol Exp Ther. 1992 Dec;263(3):1302-7. PubMed PMID: 1469636.