YM 534

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 341162

CAS#: 95923-66-3

Description: YM 534 is a biochemical.

Chemical Structure

YM 534
CAS# 95923-66-3

Theoretical Analysis

MedKoo Cat#: 341162
Name: YM 534
CAS#: 95923-66-3
Chemical Formula: C24H36N2O4
Exact Mass: 416.2675
Molecular Weight: 416.562
Elemental Analysis: C, 69.20; H, 8.71; N, 6.73; O, 15.36

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: YM 534; YM-534; YM534.

IUPAC/Chemical Name: Hexanoic acid, 6-(4-((5-(1H-imidazol-1-yl)pentyl)oxy)phenoxy)-2,2-dimethyl-, ethyl ester


InChi Code: InChI=1S/C24H36N2O4/c1-4-28-23(27)24(2,3)14-6-9-19-30-22-12-10-21(11-13-22)29-18-8-5-7-16-26-17-15-25-20-26/h10-13,15,17,20H,4-9,14,16,18-19H2,1-3H3

SMILES Code: C(C(CCCCOc1ccc(cc1)OCCCCCn1ccnc1)(C)C)(=O)OCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 416.562 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Kanamaru R, Ishioka C, Konishi Y, Ishikawa S, Shibata H, Wakui A. [DNA damage and anticancer effect]. Gan To Kagaku Ryoho. 1990 Mar;17(3 Pt 2):517-23. Review. Japanese. PubMed PMID: 2181939.

2: Kanamaru R, Ishioka C, Konishi Y, Ishikawa A, Shibata H, Wakui A. Damage to DNA strand and the effects of anticancer drugs. Sci Rep Res Inst Tohoku Univ Med. 1989 Dec;36(1-4):29-36. PubMed PMID: 2640065.

3: Kanamaru R, Ishioka C, Konishi Y, Ishikawa A, Shibata H, Wakui A. Mechanism of action of the synthetic imidazole compound YM 534 on human promyelocytic leukemia line HL-60 cells. Anticancer Drug Des. 1989 Aug;4(2):137-44. PubMed PMID: 2803462.

4: Sato S, Watanabe Y, Okamura K, Hamanaka R, Mori T, Kohno K, Kuwano M. Potentiation of vincristine and actinomycin D by a new synthetic imidazole anti-tumor agent YM534 active against human cancer cells and multidrug-resistant cells. Anticancer Drug Des. 1989 Aug;4(2):125-35. PubMed PMID: 2803461.