WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 341162
Description: YM 534 is a biochemical.
MedKoo Cat#: 341162
Name: YM 534
Chemical Formula: C24H36N2O4
Exact Mass: 416.2675
Molecular Weight: 416.562
Elemental Analysis: C, 69.20; H, 8.71; N, 6.73; O, 15.36
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: YM 534; YM-534; YM534.
IUPAC/Chemical Name: Hexanoic acid, 6-(4-((5-(1H-imidazol-1-yl)pentyl)oxy)phenoxy)-2,2-dimethyl-, ethyl ester
InChi Key: OFCXZLBZYMCRLB-UHFFFAOYSA-N
InChi Code: InChI=1S/C24H36N2O4/c1-4-28-23(27)24(2,3)14-6-9-19-30-22-12-10-21(11-13-22)29-18-8-5-7-16-26-17-15-25-20-26/h10-13,15,17,20H,4-9,14,16,18-19H2,1-3H3
SMILES Code: C(C(CCCCOc1ccc(cc1)OCCCCCn1ccnc1)(C)C)(=O)OCC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 416.562 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kanamaru R, Ishioka C, Konishi Y, Ishikawa S, Shibata H, Wakui A. [DNA damage and anticancer effect]. Gan To Kagaku Ryoho. 1990 Mar;17(3 Pt 2):517-23. Review. Japanese. PubMed PMID: 2181939.
2: Kanamaru R, Ishioka C, Konishi Y, Ishikawa A, Shibata H, Wakui A. Damage to DNA strand and the effects of anticancer drugs. Sci Rep Res Inst Tohoku Univ Med. 1989 Dec;36(1-4):29-36. PubMed PMID: 2640065.
3: Kanamaru R, Ishioka C, Konishi Y, Ishikawa A, Shibata H, Wakui A. Mechanism of action of the synthetic imidazole compound YM 534 on human promyelocytic leukemia line HL-60 cells. Anticancer Drug Des. 1989 Aug;4(2):137-44. PubMed PMID: 2803462.
4: Sato S, Watanabe Y, Okamura K, Hamanaka R, Mori T, Kohno K, Kuwano M. Potentiation of vincristine and actinomycin D by a new synthetic imidazole anti-tumor agent YM534 active against human cancer cells and multidrug-resistant cells. Anticancer Drug Des. 1989 Aug;4(2):125-35. PubMed PMID: 2803461.